Calan sr and Synthroid drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Calan sr (verapamil hydrochloride) and Synthroid (levothyroxine sodium). Common drug interactions include contusion among females and blindness unilateral among males.

The phase IV clinical study analyzes what interactions people have when they take Calan sr and Synthroid. It is created by eHealthMe based on reports of 47 people who take the same drugs from the FDA, and is updated regularly.

What is Calan sr?

Calan sr has active ingredients of verapamil hydrochloride. It is often used in high blood pressure. eHealthMe is studying from 589 Calan sr users. Check the latest studies of Calan sr.

What is Synthroid?

Synthroid has active ingredients of levothyroxine sodium. It is often used in hypothyroidism. eHealthMe is studying from 249,202 Synthroid users. Check the latest studies of Synthroid.

On Aug, 07, 2026

47 people who take Calan sr and Synthroid together, and have interactions are studied.

Calan sr and Synthroid drug interactions.

What are the common drug interactions of Calan Sr and Synthroid, by gender? *:

female:

Contusion (a type of hematoma of tissue in which capillaries)
Cough
Dehydration (dryness resulting from the removal of water)
Diplopia (double vision)
Drug intolerance (drug sensitivity)
Dry eye (lack of adequate tears)
Dry skin
Dry throat
Dyspepsia (indigestion)
Dyspnoea exertional (breathlessness or shortness of breath)

male:

Blindness unilateral
Eye swelling
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
Dizziness
Drug hypersensitivity
Dysphonia (speech disorder attributable to a disorder of phonation)
Dyspnoea (difficult or laboured respiration)
Essential hypertension (primary hypertension)

What are the common drug interactions of Calan Sr and Synthroid, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)

30-39:

n/a

40-49:

Oedema (fluid collection in tissue)
Dizziness

50-59:

Spinal fracture (fracture in one of vertebrae)
Blood pressure decreased
Confusion
Confusional state
Dizziness
Dry mouth
Fatigue (feeling of tiredness)
Malaise (a feeling of general discomfort or uneasiness)
Tinnitus (a ringing in the ears)
Vertigo

60+:

Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Chest discomfort
Crying
Ear disorder
Electrocardiogram st segment depression
Loss of consciousness
Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
Nervousness
Stress

What are the existing conditions these people have? *

Thyroid Diseases: 11 people, 23.40%
Hiatal Hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm): 8 people, 17.02%
Heart Rate Increased: 8 people, 17.02%
Primary Myelofibrosis (primary disorder of the bone marrow): 5 people, 10.64%
Pain: 4 people, 8.51%
Multiple Myeloma (cancer of the plasma cells): 4 people, 8.51%
Hypersensitivity: 4 people, 8.51%
Arrhythmias (irregular heartbeat): 4 people, 8.51%
Neoplasm Malignant (cancer tumour): 3 people, 6.38%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 3 people, 6.38%

* Approximation only. Some reports may have incomplete information.

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