Calan sr and Zantac drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Calan sr (verapamil hydrochloride) and Zantac (ranitidine hydrochloride). Common drug interactions include fibula fracture among females and angina pectoris among males.

The phase IV clinical study analyzes what interactions people have when they take Calan sr and Zantac. It is created by eHealthMe based on reports of 19 people who take the same drugs from the FDA, and is updated regularly.

What is Calan sr?

Calan sr has active ingredients of verapamil hydrochloride. It is often used in high blood pressure. eHealthMe is studying from 589 Calan sr users. Check the latest studies of Calan sr.

What is Zantac?

Zantac has active ingredients of ranitidine hydrochloride. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 434,161 Zantac users. Check the latest studies of Zantac.

On Aug, 04, 2026

19 people who take Calan sr and Zantac together, and have interactions are studied.

What are the common drug interactions of Calan Sr and Zantac, by gender? *:

female:

Fibula fracture
Flatulence (flatus expelled through the anus)
Foot fracture
Glossitis (infection of tongue with soreness)
Glossodynia (a burning or painful sensation in the tongue)
Gout (uric acid crystals building up in the body)
Hand fracture
Head injury
Heart rate increased
Humerus fracture (injury to the upper arm bone)

male:

Angina pectoris (chest pain due to ischemia of the heart muscle)
Anxiety
Essential hypertension (primary hypertension)
Fall
Gout (uric acid crystals building up in the body)
Hepatitis (inflammation of the liver)
Humerus fracture (injury to the upper arm bone)
Hyperlipidaemia (presence of excess lipids in the blood)
Joint dislocation (a joint position is changed from normal position)
Limb injury

What are the common drug interactions of Calan Sr and Zantac, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Drug hypersensitivity
Urticaria (rash of round, red welts on the skin that itch intensely)

50-59:

Fatigue (feeling of tiredness)
Fear, focus
Headache (pain in head)
Influenza like illness
Nasopharyngitis (inflammation of the nasopharynx)
Pain
Ventricular fibrillation (abnormally irregular heart rhythm)
Ventricular hypertrophy (enlargement of ventricles (lower chambers) in the heart)
Anxiety
Aortic atherosclerosis (degenerative process of aortic arteries)

60+:

Fall
Angina pectoris (chest pain due to ischemia of the heart muscle)
Asthma
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Essential hypertension (primary hypertension)
Gout (uric acid crystals building up in the body)
Humerus fracture (injury to the upper arm bone)
Hyperlipidaemia (presence of excess lipids in the blood)
Joint dislocation (a joint position is changed from normal position)
Limb injury

What are the existing conditions these people have? *

Pain: 2 people, 10.53%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 2 people, 10.53%
Stress And Anxiety: 2 people, 10.53%
Muscle Spasms (muscle contraction): 2 people, 10.53%
Nausea (feeling of having an urge to vomit): 2 people, 10.53%
Gastritis (inflammation of stomach): 1 person, 5.26%
Hiatal Hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm): 1 person, 5.26%
Heart Rate Irregular: 1 person, 5.26%
Headache (pain in head): 1 person, 5.26%
Gout (uric acid crystals building up in the body): 1 person, 5.26%

* Approximation only. Some reports may have incomplete information.

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