Calcium ascorbate and Ultram drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Calcium ascorbate (vitamin c (ascorbic acid)) and Ultram (tramadol hydrochloride). Common drug interactions include burning sensation among females and abdominal pain among males.

The phase IV clinical study analyzes what interactions people have when they take Calcium ascorbate and Ultram. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Calcium ascorbate?

Calcium ascorbate has active ingredients of vitamin c (ascorbic acid). eHealthMe is studying from 1,018 Calcium ascorbate users. Check the latest studies of Calcium ascorbate.

What is Ultram?

Ultram has active ingredients of tramadol hydrochloride. It is often used in pain. eHealthMe is studying from 28,425 Ultram users. Check the latest studies of Ultram.



On Jul, 09, 2026

13 people who take Calcium ascorbate and Ultram together, and have interactions are studied.

Calcium ascorbate and Ultram drug interactions.

What are the common drug interactions of Calcium Ascorbate and Ultram, by gender? *:

female:

  1. Burning sensation
  2. Cardiac disorder
  3. Carpal tunnel syndrome (nerve compression at wrist results numbness weakness, pain , swelling)
  4. Dyspnoea (difficult or laboured respiration)
  5. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  6. Headache (pain in head)
  7. Hospitalisation
  8. Hypertension (high blood pressure)
  9. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
  10. Polycystic ovaries (cysts in the ovaries that occurs when the follicle stops developing)

male:

  1. Abdominal pain
  2. Abnormal loss of weight
  3. Colitis (inflammation of colon)
  4. Diarrhoea
  5. Failure to thrive (inadequate weight gain and physical growth in children)
  6. Fatigue (feeling of tiredness)
  7. Hypertension (high blood pressure)

What are the common drug interactions of Calcium Ascorbate and Ultram, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Cholecystitis chronic (long lasting infection of gallbladder)
  2. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  3. Pulmonary embolism (blockage of the main artery of the lung)

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Ejection fraction (the percentage of blood that is pumped out of a filled ventricle as a result of a heartbeat)
  2. Adverse event
  3. Asthma
  4. Burning sensation
  5. Cardiac disorder
  6. Carpal tunnel syndrome (nerve compression at wrist results numbness weakness, pain , swelling)
  7. Dyspnoea (difficult or laboured respiration)
  8. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  9. Headache (pain in head)
  10. Hospitalisation

60+:

  1. Abdominal pain
  2. Abnormal loss of weight
  3. Colitis (inflammation of colon)
  4. Diarrhoea
  5. Failure to thrive (inadequate weight gain and physical growth in children)
  6. Fatigue (feeling of tiredness)
  7. Hypertension (high blood pressure)
  8. Renal failure acute (rapid kidney dysfunction)
  9. Urinary tract infection
  10. Atelectasis (partial or complete collapse of the lung)

What are the existing conditions these people have? *

  1. Asthma: 4 people, 30.77%
  2. Prostate Cancer Metastatic: 2 people, 15.38%
  3. Chronic Inflammatory Demyelinating Polyradiculoneuropathy (long lasting infection of nerves outside brain and spinal cord): 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Calcium ascorbate and Ultram?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Calcium ascorbate and Ultram:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Calcium ascorbate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Ultram:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Calcium ascorbate and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Ultram and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on vitamin c (ascorbic acid) and tramadol hydrochloride (the active ingredients of Calcium ascorbate and Ultram, respectively), and Calcium ascorbate and Ultram (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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