Calcium and Ambisome drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Calcium (calcium) and Ambisome (amphotericin b). Common drug interactions include atrial fibrillation among females and toxic epidermal necrolysis among males.

The phase IV clinical study analyzes what interactions people have when they take Calcium and Ambisome. It is created by eHealthMe based on reports of 90 people who take the same drugs from the FDA, and is updated regularly.

What is Calcium?

Calcium has active ingredients of calcium. It is often used in osteoporosis. eHealthMe is studying from 184,201 Calcium users. Check the latest studies of Calcium.

What is Ambisome?

Ambisome has active ingredients of amphotericin b. eHealthMe is studying from 7,934 Ambisome users. Check the latest studies of Ambisome.



On Jul, 10, 2026

90 people who take Calcium and Ambisome together, and have interactions are studied.

Calcium and Ambisome drug interactions.

What are the common drug interactions of Calcium and Ambisome, by gender? *:

female:

  1. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  2. Bacterial infection
  3. Fungal infection
  4. Cardiac failure congestive
  5. Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)
  6. Erythema (redness of the skin)
  7. Purpura (purplish discoloration of the skin)
  8. Respiratory distress (difficulty in breathing)
  9. Anal inflammation
  10. Bk virus infection

male:

  1. Toxic epidermal necrolysis (a rare, life-threatening skin condition that is usually caused by a reaction to drugs causes wide spread skin destruction)
  2. Graft versus host disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body)
  3. Anaemia (lack of blood)
  4. Bronchopulmonary aspergillosis (lung disorder caused by aspergillus fungi)
  5. Chronic lymphocytic leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell))
  6. Confusional state
  7. Dysphagia (a condition in which swallowing is difficult or painful)
  8. General physical health deterioration (weak health status)
  9. Infection
  10. Lymphadenopathy (disease or enlargement of lymph nodes)

What are the common drug interactions of Calcium and Ambisome, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

  1. Atelectasis (partial or complete collapse of the lung)
  2. Febrile neutropenia (fever with reduced white blood cells)
  3. Pneumothorax (the presence of air or gas in the cavity between the lungs and the chest wall, causing collapse of the lung)
  4. Postoperative thoracic procedure complication

10-19:

  1. Stomatitis (inflammation of mucous membrane of mouth)
  2. Acidosis (build-up of carbon dioxide in the blood)
  3. Cardiac arrest
  4. Encephalopathy (functioning of the brain is affected by some agent or condition)
  5. Enterocolitis (inflammation of the digestive tract, involving enteritis of the small intestine and colitis of the colon)
  6. Hypercalcaemia (elevated calcium (ca+) level in the blood)
  7. Hypocalcaemia (levels of calcium in blood serum are abnormally low)
  8. Hypotension (abnormally low blood pressure)
  9. Posterior reversible encephalopathy syndrome (posterior reversible encephalopathy syndrome (pres), also known as reversible posterior leukoencephalopathy syndrome (rpls), is a syndrome characterized by headache, confusion, seizures and visual loss)
  10. Respiratory failure (inadequate gas exchange by the respiratory system)

20-29:

  1. Pancreatitis (inflammation of pancreas)
  2. Anaemia (lack of blood)
  3. Anaphylactoid reaction (type of anaphylaxis that does not involve an allergic reaction but is due to direct mast cell degranulation)
  4. B-cell type acute leukaemia (cancer of the white blood cells)
  5. Bilirubin conjugated increased
  6. Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
  7. Blood chloride increased
  8. Blood creatinine decreased
  9. Blood glucose increased
  10. Blood magnesium decreased

30-39:

  1. Blood bicarbonate increased
  2. Blood ph decreased
  3. Blood ph increased
  4. Bone marrow failure
  5. Febrile neutropenia (fever with reduced white blood cells)
  6. Lactobacillus infection
  7. Scleral haemorrhage (bleeding from sclera)
  8. Tachycardia (a heart rate that exceeds the range of 100 beats/min)
  9. Alanine aminotransferase increased
  10. Arthralgia (joint pain)

40-49:

  1. Toxic epidermal necrolysis (a rare, life-threatening skin condition that is usually caused by a reaction to drugs causes wide spread skin destruction)
  2. Graft versus host disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body)
  3. Sepsis (a severe blood infection that can lead to organ failure and death)
  4. Lymphadenopathy (disease or enlargement of lymph nodes)
  5. Pneumonia
  6. Cardiac failure
  7. Scrotal infection (infection in scrotum area)
  8. Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
  9. Coagulopathy (blood's ability to clot is impaired)
  10. Conjunctivitis (pink eye)

50-59:

  1. Pulmonary embolism (blockage of the main artery of the lung)
  2. Respiratory failure (inadequate gas exchange by the respiratory system)
  3. Lung infection
  4. Pulmonary cavitation (cavity in the lung)
  5. Febrile neutropenia (fever with reduced white blood cells)
  6. Haemorrhagic erosive gastritis (bleeding from peptic ulcer disease)
  7. Infection
  8. Hypokalaemia (low potassium)
  9. Encephalopathy (functioning of the brain is affected by some agent or condition)
  10. Neutropenia (an abnormally low number of neutrophils)

60+:

  1. Neutropenia (an abnormally low number of neutrophils)
  2. Pneumonia
  3. Erythema nodosum (skin inflammation that results in reddish, painful, tender lumps most commonly located in the front of the legs below)
  4. General physical health deterioration (weak health status)
  5. Hypertension (high blood pressure)
  6. Hyperuricaemia (level of uric acid in the blood that is abnormally high)
  7. Hypocalcaemia (levels of calcium in blood serum are abnormally low)
  8. Hypokalaemia (low potassium)
  9. Infection
  10. Muscle haemorrhage (bleeding in muscle)

What are the existing conditions these people have? *

  1. Nausea (feeling of having an urge to vomit): 36 people, 40.00%
  2. Pain: 32 people, 35.56%
  3. Infection: 29 people, 32.22%
  4. Blood Calcium Decreased: 25 people, 27.78%
  5. Urinary Tract Infection: 25 people, 27.78%
  6. Hypotension (abnormally low blood pressure): 24 people, 26.67%
  7. Oedema (fluid collection in tissue): 24 people, 26.67%
  8. Blood Magnesium Decreased: 22 people, 24.44%
  9. Hypokalemia (low potassium): 22 people, 24.44%
  10. Depression: 21 people, 23.33%

* Approximation only. Some reports may have incomplete information.

Do you take Calcium and Ambisome?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Calcium and Ambisome:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Calcium:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Ambisome:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Calcium and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Ambisome and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on calcium and amphotericin b (the active ingredients of Calcium and Ambisome, respectively), and Calcium and Ambisome (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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