Calcium and Comtan drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Calcium (calcium) and Comtan (entacapone). Common drug interactions include blood pressure fluctuation among females and death among males.
The phase IV clinical study analyzes what interactions people have when they take Calcium and Comtan. It is created by eHealthMe based on reports of 40 people who take the same drugs from the FDA, and is updated regularly.
What is Calcium?
Calcium has active ingredients of calcium. It is often used in osteoporosis. eHealthMe is studying from 184,201 Calcium users. Check the latest studies of Calcium.
What is Comtan?
Comtan has active ingredients of entacapone. It is often used in parkinson's disease. eHealthMe is studying from 3,979 Comtan users. Check the latest studies of Comtan.
40 people who take Calcium and Comtan together, and have interactions are studied.

What are the common drug interactions of Calcium and Comtan, by gender? *:
female:
- Blood pressure fluctuation
- Cystitis (inflammation of the wall of the bladder)
- Hypertension (high blood pressure)
- Urine viscosity increased
- Agitation (state of anxiety or nervous excitement)
- Death
- Dehydration (dryness resulting from the removal of water)
- Device dislocation
- Drug ineffective
- Infection
male:
- Death
- Depression
- Dyspnoea (difficult or laboured respiration)
- Emotional distress
- Essential hypertension (primary hypertension)
- Fall
- Gait disturbance
- Hypertension (high blood pressure)
- Hypokinesia (decreased bodily movement)
- Nephrolithiasis (calculi in the kidneys)
What are the common drug interactions of Calcium and Comtan, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
n/a
50-59:
- Affective disorder (mental disorder)
- Anxiety
- Emotional distress
- Fear
- Impulse-control disorder
- Obsessive-compulsive disorder (an anxiety disorder characterized by intrusive thoughts that produce uneasiness, apprehension, fear, or worry;)
- Pain
- Pathological gambling
- Injection site haematoma (localized swelling filled with blood at injection site)
60+:
- Hallucination (an experience involving the perception of something not present)
- Pneumonia
- Agitation (state of anxiety or nervous excitement)
- Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
- Anaemia (lack of blood)
- Aortic valve disease
- Arrhythmia (irregular heartbeat)
- Benign prostatic hyperplasia (benign enlargement of the prostate)
- Cervical spinal stenosis (narrowing of the spinal canal in the neck)
- Chest pain
What are the existing conditions these people have? *
- Hallucinations (sensations that appear real but are created by your mind): 8 people, 20.00%
- Delusion (a false belief or opinion): 8 people, 20.00%
- Pain: 7 people, 17.50%
- Constipation: 6 people, 15.00%
- Stress And Anxiety: 5 people, 12.50%
- Sleep Disorder: 5 people, 12.50%
- Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 5 people, 12.50%
- Insomnia (sleeplessness): 4 people, 10.00%
- Gout (uric acid crystals building up in the body): 4 people, 10.00%
- Swelling: 4 people, 10.00%
* Approximation only. Some reports may have incomplete information.
Do you take Calcium and Comtan?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Calcium and Comtan:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Calcium:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Comtan:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Calcium and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Comtan and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on calcium and entacapone (the active ingredients of Calcium and Comtan, respectively), and Calcium and Comtan (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
Recent studies on eHealthMe:
- Could Estrace cause Upper-Airway Cough Syndrome? - 12 seconds ago
- Could Ultracet cause Delusion? - 12 seconds ago
- Could Furosemide cause Endometrial Cancer? - 18 seconds ago
- Crohn'S Disease and Peritonitis - 27 seconds ago
- Could Fentanyl-100 cause Jaw Disorder? - 28 seconds ago
- Amphetamine Sulfate vs. Oxycontin, side effect and effectiveness comparison - 37 seconds ago
- Could Invega cause Hyperhidrosis? - 38 seconds ago
- Could Xeljanz cause Vitreous Detachment? - 38 seconds ago
- Could Xeljanz cause Conjunctivitis? - 39 seconds ago
- Could Lactulose cause Metabolic Alkalosis? - 41 seconds ago