Calcium and Hectorol drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Calcium (calcium) and Hectorol (doxercalciferol). Common drug interactions include nephrogenic systemic fibrosis among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Calcium and Hectorol. It is created by eHealthMe based on reports of 23 people who take the same drugs from the FDA, and is updated regularly.

What is Calcium?

Calcium has active ingredients of calcium. It is often used in osteoporosis. eHealthMe is studying from 184,201 Calcium users. Check the latest studies of Calcium.

What is Hectorol?

Hectorol has active ingredients of doxercalciferol. eHealthMe is studying from 1,815 Hectorol users. Check the latest studies of Hectorol.



On Jul, 29, 2026

23 people who take Calcium and Hectorol together, and have interactions are studied.

Calcium and Hectorol drug interactions.

What are the common drug interactions of Calcium and Hectorol, by gender? *:

female:

  1. Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)
  2. Renal failure (kidney dysfunction)
  3. Chronic kidney disease
  4. Platelet count decreased
  5. Hypoparathyroidism (inadequate secretion of parathyroid hormone resulting in abnormally low levels of calcium in the blood)
  6. Axonal neuropathy (dysfunction of axon nerves)
  7. Blood glucose increased
  8. Cervical vertebral fracture
  9. Death
  10. Dehydration (dryness resulting from the removal of water)

male:

  1. Chronic kidney disease
  2. Renal failure (kidney dysfunction)
  3. Decreased activity
  4. Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
  5. Loss of employment
  6. Mobility decreased (ability to move is reduced)
  7. Quality of life decreased
  8. Social problem
  9. Ageusia (loss of taste functions of the tongue)
  10. Anaemia of chronic disease

What are the common drug interactions of Calcium and Hectorol, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Chronic kidney disease
  2. Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)
  3. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  4. Anxiety
  5. Decreased activity
  6. Emotional distress
  7. Fatigue (feeling of tiredness)
  8. Loss of employment
  9. Mobility decreased (ability to move is reduced)
  10. Pain

40-49:

  1. Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)

50-59:

  1. Platelet count decreased

60+:

  1. Asthenia (weakness)
  2. Chronic kidney disease
  3. Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall)
  4. Fall
  5. Hunger
  6. Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
  7. Hypertensive crisis
  8. Hypocalcaemia (levels of calcium in blood serum are abnormally low)
  9. Insomnia (sleeplessness)
  10. Nausea (feeling of having an urge to vomit)

What are the existing conditions these people have? *

  1. Multiple Myeloma (cancer of the plasma cells): 6 people, 26.09%
  2. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 21.74%
  3. Pain: 4 people, 17.39%
  4. Headache (pain in head): 3 people, 13.04%
  5. Hiv Infection: 2 people, 8.70%
  6. High Blood Pressure: 2 people, 8.70%
  7. Anaemia (lack of blood): 2 people, 8.70%

* Approximation only. Some reports may have incomplete information.

Do you take Calcium and Hectorol?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Calcium and Hectorol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Calcium:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Hectorol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Calcium and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Hectorol and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on calcium and doxercalciferol (the active ingredients of Calcium and Hectorol, respectively), and Calcium and Hectorol (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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