Campral and Clonazepam drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Campral (acamprosate calcium) and Clonazepam (clonazepam). Common drug interactions include asthenia among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Campral and Clonazepam. It is created by eHealthMe based on reports of 41 people who take the same drugs from the FDA, and is updated regularly.

What is Campral?

Campral has active ingredients of acamprosate calcium. It is often used in alcoholism. eHealthMe is studying from 1,007 Campral users. Check the latest studies of Campral.

What is Clonazepam?

Clonazepam has active ingredients of clonazepam. It is often used in stress and anxiety. eHealthMe is studying from 146,270 Clonazepam users. Check the latest studies of Clonazepam.



On Jul, 07, 2026

41 people who take Campral and Clonazepam together, and have interactions are studied.

Campral and Clonazepam drug interactions.

What are the common drug interactions of Campral and Clonazepam, by gender? *:

female:

  1. Asthenia (weakness)
  2. Electrocardiogram qt prolonged
  3. Hyperhidrosis (abnormally increased sweating)
  4. Malaise (a feeling of general discomfort or uneasiness)
  5. Nausea (feeling of having an urge to vomit)
  6. Ventricular fibrillation (abnormally irregular heart rhythm)
  7. Hypokalaemia (low potassium)
  8. Torsade de pointes (a abnormal heart rate with abnormal beating pattern)
  9. Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood)
  10. Hospitalisation

male:

  1. Chronic kidney disease
  2. Nephrogenic anaemia (anaemia due to kidney disease)
  3. Nausea (feeling of having an urge to vomit)
  4. Renal failure (kidney dysfunction)
  5. Weight decreased
  6. White blood cell count decreased
  7. Renal injury (kidney injury)
  8. Ammonia increased
  9. Asperger's disorder (autism spectrum disorder that affects language and behavioural development in children)
  10. Decreased appetite

What are the common drug interactions of Campral and Clonazepam, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Aggression
  2. Depression
  3. Injury
  4. Suicide attempt

30-39:

  1. Chronic kidney disease
  2. Nephrogenic anaemia (anaemia due to kidney disease)
  3. Renal injury (kidney injury)
  4. Ammonia increased
  5. Hepatic encephalopathy (spectrum of neuropsychiatric abnormalities in patients with liver failure)
  6. Renal failure (kidney dysfunction)
  7. White blood cell count decreased

40-49:

  1. Asperger's disorder (autism spectrum disorder that affects language and behavioural development in children)
  2. Chronic kidney disease
  3. Decreased appetite
  4. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  5. Emotional distress
  6. Injury
  7. Lack of spontaneous speech
  8. Malaise (a feeling of general discomfort or uneasiness)
  9. Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
  10. Nausea (feeling of having an urge to vomit)

50-59:

  1. Asthenia (weakness)
  2. Hospitalisation
  3. Cardioversion
  4. Electrolyte imbalance
  5. White blood cell count decreased
  6. Blood glucose increased
  7. Breast cancer
  8. Decreased appetite
  9. Drug ineffective
  10. Headache (pain in head)

60+:

  1. Hypothermia (body temperature drops below the required temperature for normal metabolism and body functions)

What are the existing conditions these people have? *

  1. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 12.20%
  2. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 4 people, 9.76%
  3. Infection: 4 people, 9.76%
  4. Pain: 3 people, 7.32%
  5. Obsessive-Compulsive Disorder (an anxiety disorder characterized by intrusive thoughts that produce uneasiness, apprehension, fear, or worry;): 3 people, 7.32%
  6. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 3 people, 7.32%

* Approximation only. Some reports may have incomplete information.

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Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Campral and Clonazepam:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Campral:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Clonazepam:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Campral and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Clonazepam and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on acamprosate calcium and clonazepam (the active ingredients of Campral and Clonazepam, respectively), and Campral and Clonazepam (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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