Canasa and Dilaudid drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Canasa (mesalamine) and Dilaudid (hydromorphone hydrochloride). Common drug interactions include adrenal insufficiency among females and abdominal pain upper among males.
The phase IV clinical study analyzes what interactions people have when they take Canasa and Dilaudid. It is created by eHealthMe based on reports of 17 people who take the same drugs from the FDA, and is updated regularly.
What is Canasa?
Canasa has active ingredients of mesalamine. It is often used in ulcerative colitis. eHealthMe is studying from 1,676 Canasa users. Check the latest studies of Canasa.
What is Dilaudid?
Dilaudid has active ingredients of hydromorphone hydrochloride. It is often used in pain. eHealthMe is studying from 96,466 Dilaudid users. Check the latest studies of Dilaudid.
17 people who take Canasa and Dilaudid together, and have interactions are studied.

What are the common drug interactions of Canasa and Dilaudid, by gender? *:
female:
- Adrenal insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids)
- Adrenocortical insufficiency acute (suddenly adrenal glands do not produce adequate amounts of steroid hormones)
- Anaemia (lack of blood)
- Anxiety
- Aphasia (damage to the parts of the brain that control language)
- Arthralgia (joint pain)
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
- Cardiac failure congestive
- Confusional state
- Fall
male:
- Abdominal pain upper
- Arthralgia (joint pain)
- Crohn's disease (a condition that causes inflammation of the gastrointestinal tract)
- Injection site pain
- Intestinal obstruction
- Pain in extremity
- Post procedural complication
What are the common drug interactions of Canasa and Dilaudid, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Abdominal pain
- Abdominal pain upper
- Adrenal insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids)
- Adrenocortical insufficiency acute (suddenly adrenal glands do not produce adequate amounts of steroid hormones)
- Migraine (headache)
- Nausea (feeling of having an urge to vomit)
30-39:
n/a
40-49:
- Nasopharyngitis (inflammation of the nasopharynx)
- Neck mass (mass in neck)
- Ovarian cyst (fluid filled sac of the ovary)
- Rhinorrhoea (watery mucus discharge from the nose)
- Uterine leiomyoma (uterine benign tumour derived from smooth muscle)
- Abdominal pain upper
- Body temperature increased
- Breast mass
- Cough
- Headache (pain in head)
50-59:
- Anaemia (lack of blood)
- Angina pectoris (chest pain due to ischemia of the heart muscle)
- Anxiety
- Aphasia (damage to the parts of the brain that control language)
- Arthralgia (joint pain)
- Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
- Blood chloride decreased
- Blood glucose increased
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
- Cardiac failure congestive
60+:
- Arthralgia (joint pain)
- Anaemia (lack of blood)
- Fall
- Haemorrhoids (a swollen vein or group of veins in the region of the anus)
- Hallucination (an experience involving the perception of something not present)
- Injury
- Nausea (feeling of having an urge to vomit)
- Rectal haemorrhage (bleeding from anus)
- Transient ischaemic attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow))
- Cough
What are the existing conditions these people have? *
- Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 3 people, 17.65%
- Short-Bowel Syndrome (a condition in which the body cannot absorb enough fluids and nutrients because part of the small intestine is missing): 2 people, 11.76%
- Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 1 person, 5.88%
- Migraine (headache): 1 person, 5.88%
- Metastatic Malignant Melanoma (spreadable cancer tumour of melanine): 1 person, 5.88%
- Haemorrhage (bleeding): 1 person, 5.88%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 5.88%
- Depression: 1 person, 5.88%
- Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 1 person, 5.88%
- Anaemia (lack of blood): 1 person, 5.88%
* Approximation only. Some reports may have incomplete information.
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Canasa and Dilaudid:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Canasa:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Dilaudid:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Canasa and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Dilaudid and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Jacobsson H, Eriksen J, Karlén P, "Mesalazine-induced renal calculi", The American journal of case reports, 2015 Jan .
- Jacobsson H, Eriksen J, Karlén P, "Mesalazine-induced renal calculi", The American journal of case reports, 2015 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on mesalamine and hydromorphone hydrochloride (the active ingredients of Canasa and Dilaudid, respectively), and Canasa and Dilaudid (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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