Cancidas and Lopurin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Cancidas (caspofungin acetate) and Lopurin (allopurinol). Common drug interactions include diarrhoea among females and pneumonia among males.

The phase IV clinical study analyzes what interactions people have when they take Cancidas and Lopurin. It is created by eHealthMe based on reports of 88 people who take the same drugs from the FDA, and is updated regularly.

What is Cancidas?

Cancidas has active ingredients of caspofungin acetate. eHealthMe is studying from 4,879 Cancidas users. Check the latest studies of Cancidas.

What is Lopurin?

Lopurin has active ingredients of allopurinol. It is often used in gout. eHealthMe is studying from 190,798 Lopurin users. Check the latest studies of Lopurin.

On Aug, 04, 2026

88 people who take Cancidas and Lopurin together, and have interactions are studied.

What are the common drug interactions of Cancidas and Lopurin, by gender? *:

female:

Diarrhoea
Intestinal perforation (complete penetration of the wall of the intestine)
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Venoocclusive disease (small veins in the liver are obstructed)
Cholestasis (a condition where bile cannot flow from the liver to the duodenum)
Peritonitis (inflammation of the peritoneum, the thin tissue that lines the inner wall of the abdomen and covers most of the abdominal organs)
Renal failure acute (rapid kidney dysfunction)
Sepsis (a severe blood infection that can lead to organ failure and death)
Septic shock (shock due to blood infection)
Haematoma (collection of blood outside the blood vessels)

male:

Pneumonia
Acute respiratory failure
Vertigo
Pneumonitis (inflammation of the walls of the alveoli in the lungs)
Hypovolaemic shock (shock caused by severe blood or fluid loss)
Aspartate aminotransferase increased
Back pain
Cytomegalovirus infection
Cytomegalovirus test positive
Gamma-glutamyltransferase increased

What are the common drug interactions of Cancidas and Lopurin, by age (0-1 to 60+)? *:

0-1:

Cardiac failure
Prerenal failure
Respiratory failure (inadequate gas exchange by the respiratory system)

2-9:

n/a

10-19:

Dilatation intrahepatic duct acquired
Hepatotoxicity (chemical-driven liver damage)
Venoocclusive disease (small veins in the liver are obstructed)
Pneumonitis (inflammation of the walls of the alveoli in the lungs)
Alanine aminotransferase increased
Arthralgia (joint pain)
Back pain
Blood alkaline phosphatase increased
Blood bilirubin increased
Congestive cardiomyopathy (weakening of heart muscle)

20-29:

Febrile neutropenia (fever with reduced white blood cells)
Hyperbilirubinaemia (excess of bilirubin in the blood)
Oesophagitis (inflammation of oesophagus)
Infection
Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
Haemorrhagic diathesis (bleeding tendency)
Hepatic lesion
Increased tendency to bruise (increased tendency to injure the underlying soft tissue or bone)
Liver abscess (pus in liver)
Mucosal inflammation (infection of mucous membrane)

30-39:

Acute promyelocytic leukaemia (cancer of the blood and bone marrow)
Acute respiratory failure
Alanine aminotransferase increased
Aspartate aminotransferase increased
Aspergillosis (an infection caused by a fungus called aspergillus)
Bacteria stool identified
Bronchopulmonary aspergillosis (lung disorder caused by aspergillus fungi)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Cytomegalovirus infection
Diastolic dysfunction

40-49:

Acute generalised exanthematous pustulosis (acute febrile drug eruption)
Cholestasis (a condition where bile cannot flow from the liver to the duodenum)
Cytolytic hepatitis (dissolution or destruction of a liver cell)
Diarrhoea
Drug toxicity
Fungal oesophagitis (fungal inflammation of the oesophagus)
Hepatitis cholestatic (flow of bile from the liver is slowed or blocked)
Hepatomegaly (abnormal enlargement of the liver)
Hepatosplenomegaly (enlargement of both the liver and the spleen)
Hiv antibody positive

50-59:

Sepsis (a severe blood infection that can lead to organ failure and death)
Alanine aminotransferase increased
Cardiac arrest
Cytomegalovirus viraemia (cytomegalo virus in blood stream)
Encephalopathy (functioning of the brain is affected by some agent or condition)
Febrile neutropenia (fever with reduced white blood cells)
Gamma-glutamyltransferase increased
Hepatorenal failure (decrease in kidney function in a person with a severe liver disorder)
Metabolic encephalopathy (disorder or disease of the brain due to the body's disability to use energy)
Mucosal inflammation (infection of mucous membrane)

60+:

Pneumonia
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Renal impairment (severely reduced kidney function)
Vertigo
Diarrhoea
Febrile neutropenia (fever with reduced white blood cells)
Renal failure acute (rapid kidney dysfunction)
Sepsis (a severe blood infection that can lead to organ failure and death)
Urinary tract infection
Hypovolaemic shock (shock caused by severe blood or fluid loss)

What are the existing conditions these people have? *

Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 22 people, 25.00%
Pain: 13 people, 14.77%
High Blood Pressure: 10 people, 11.36%
Hyperuricaemia (level of uric acid in the blood that is abnormally high): 10 people, 11.36%
Oedema (fluid collection in tissue): 8 people, 9.09%
Multiple Myeloma (cancer of the plasma cells): 8 people, 9.09%
Fever: 8 people, 9.09%
Diabetes: 7 people, 7.95%
Cardiac Failure: 7 people, 7.95%
Insomnia (sleeplessness): 6 people, 6.82%

* Approximation only. Some reports may have incomplete information.

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