Cannabis and Sodium bicarbonate drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Cannabis (marijuana) and Sodium bicarbonate (sodium bicarbonate). Common drug interactions include hypokalaemia among females and osteopenia among males.

The phase IV clinical study analyzes what interactions people have when they take Cannabis and Sodium bicarbonate. It is created by eHealthMe based on reports of 18 people who take the same drugs from the FDA, and is updated regularly.

What is Cannabis?

Cannabis has active ingredients of marijuana. It is often used in stress and anxiety. eHealthMe is studying from 13,371 Cannabis users. Check the latest studies of Cannabis.

What is Sodium bicarbonate?

Sodium bicarbonate has active ingredients of sodium bicarbonate. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 27,283 Sodium bicarbonate users. Check the latest studies of Sodium bicarbonate.

On Jul, 03, 2026

18 people who take Cannabis and Sodium bicarbonate together, and have interactions are studied.

Cannabis and Sodium bicarbonate drug interactions.

What are the common drug interactions of Cannabis and Sodium Bicarbonate, by gender? *:

female:

Hypokalaemia (low potassium)
Hypoproteinaemia (too little prolactin circulating in the blood)
Intervertebral disc protrusion (spinal disc protrusion)
Panniculitis (inflammation of the subcutaneous fat)
Productive cough
Restrictive pulmonary disease (reduction in total lung capacity)
Arthralgia (joint pain)
Asthenia (weakness)
Gingival bleeding (bleeding gums)
Hepatic failure (liver failure)

male:

Osteopenia (a condition where bone mineral density is lower than normal)
Platelet count decreased
Vomiting
Abdominal pain
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Blood albumin decreased
Bone density decreased
Compression fracture (fracture due to pressure caused by injury)
Depression
Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)

What are the common drug interactions of Cannabis and Sodium Bicarbonate, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures)
Nausea (feeling of having an urge to vomit)
Vomiting

20-29:

Otitis externa (external ear infection)
Substance-induced psychotic disorder
Viral infection

30-39:

n/a

40-49:

Platelet count decreased
White blood cell count decreased

50-59:

Abdominal pain
Arteriovenous fistula site infection
Arthralgia (joint pain)
Blood albumin decreased
Body temperature increased
Chronic kidney disease
Crohn's disease (a condition that causes inflammation of the gastrointestinal tract)
Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
Diverticular perforation (serious gastrointestinal condition in which the intestine's walls are perforated)
Eye inflammation

60+:

Hypokalaemia (low potassium)
Hypoproteinaemia (too little prolactin circulating in the blood)
Lacunar infarction (a type of stroke)
Myelosuppression (a decrease in the production of blood cells)
Nasal obstruction (blockage of nose)
Panniculitis (inflammation of the subcutaneous fat)
Pyrexia (fever)
Stomatitis (inflammation of mucous membrane of mouth)
Arthralgia (joint pain)
C-reactive protein increased

What are the existing conditions these people have? *

Pneumonia: 7 people, 38.89%
Gastric Disorder (disease of stomach): 5 people, 27.78%
Hyperuricaemia (level of uric acid in the blood that is abnormally high): 4 people, 22.22%
Drug-Induced Liver Injury (diseases of the liver that are caused by physician-prescribed medications): 4 people, 22.22%
Local Anaesthesia: 4 people, 22.22%
Multiple Myeloma (cancer of the plasma cells): 4 people, 22.22%
Dyschezia (difficulty in defecating): 4 people, 22.22%
High Blood Pressure: 4 people, 22.22%
Osteoporosis (bones weak and more likely to break): 4 people, 22.22%
Glomerulonephritis Membranous (nephritis with inflammation of the capillary loops in the renal glomeruli): 2 people, 11.11%

* Approximation only. Some reports may have incomplete information.

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