Clarithromycin and Paradoxical drug reaction - a phase IV clinical study of FDA data

Summary:

Paradoxical drug reaction is reported as a side effect among people who take Clarithromycin (clarithromycin), especially for people who are male, 60+ old, have been taking the drug for 1 - 6 months also take Efavirenz, and have Mycobacterium ulcerans infection.

The phase IV clinical study analyzes which people have Paradoxical drug reaction when taking Clarithromycin. It is created by eHealthMe based on reports of 44,030 people who have side effects when taking Clarithromycin from the FDA, and is updated regularly.

What is Clarithromycin?

Clarithromycin has active ingredients of clarithromycin. It is often used in sinusitis. eHealthMe is studying from 45,044 Clarithromycin users. Check the latest studies of Clarithromycin.

What is Paradoxical drug reaction?

Paradoxical drug reaction is found to be associated with 219 drugs and 438 conditions by eHealthMe. Check the latest studies of Paradoxical drug reaction.

On Jul, 03, 2026

44,030 people reported to have side effects when taking Clarithromycin.
Among them, 109 people (0.25%) have Paradoxical drug reaction.

Could Clarithromycin cause Paradoxical drug reaction?

Among these 109 people:

How long have people been on Clarithromycin when they have Paradoxical drug reaction? *

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What is the gender of people who have Paradoxical drug reaction when taking Clarithromycin? *

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What is the age of people who have Paradoxical drug reaction when taking Clarithromycin? *

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* Approximation only. Some reports may have incomplete information.

Do you take Clarithromycin and have Paradoxical drug reaction?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Clarithromycin:

Clarithromycin (45,044 reports)

Paradoxical drug reaction treatments and more:

Paradoxical drug reaction (3,482 reports)

How severe was Paradoxical drug reaction and when was it recovered:

Paradoxical drug reaction in Clarithromycin

Expand to all the drugs that have ingredients of clarithromycin:

Paradoxical drug reaction and drugs with ingredients of clarithromycin

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Clarithromycin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Paradoxical drug reaction:

Paradoxical drug reaction (219 drugs)

Browse all the conditions that are associated with Paradoxical drug reaction:

Paradoxical drug reaction (438 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on clarithromycin (the active ingredients of Clarithromycin) and Clarithromycin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.