Cannabis and Vesicare drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Cannabis (marijuana) and Vesicare (solifenacin succinate). Common drug interactions include abdominal pain among females and multiple sclerosis among males.

The phase IV clinical study analyzes what interactions people have when they take Cannabis and Vesicare. It is created by eHealthMe based on reports of 22 people who take the same drugs from the FDA, and is updated regularly.

What is Cannabis?

Cannabis has active ingredients of marijuana. It is often used in stress and anxiety. eHealthMe is studying from 13,371 Cannabis users. Check the latest studies of Cannabis.

What is Vesicare?

Vesicare has active ingredients of solifenacin succinate. It is often used in urge incontinence. eHealthMe is studying from 30,656 Vesicare users. Check the latest studies of Vesicare.



On Jul, 29, 2026

22 people who take Cannabis and Vesicare together, and have interactions are studied.

Cannabis and Vesicare drug interactions.

What are the common drug interactions of Cannabis and Vesicare, by gender? *:

female:

  1. Abdominal pain
  2. Blood magnesium decreased
  3. Colitis ulcerative (inflammation of colon with ulcer)
  4. Cyst (a closed sac)
  5. Frequent bowel movements
  6. Haemoglobin decreased
  7. Increased tendency to bruise (increased tendency to injure the underlying soft tissue or bone)
  8. Irritable bowel syndrome
  9. Muscle spasms (muscle contraction)
  10. Nausea (feeling of having an urge to vomit)

male:

  1. Multiple sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
  2. Arthralgia (joint pain)
  3. Dyspnoea (difficult or laboured respiration)
  4. Dysstasia (difficulty in standing)
  5. Grip strength decreased
  6. Headache (pain in head)
  7. Hemiparesis (weakness on one side of the body)
  8. Hypoaesthesia (reduced sense of touch or sensation)
  9. Initial insomnia (feeling of inadequate or poor-quality sleep)
  10. Irritability

What are the common drug interactions of Cannabis and Vesicare, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Infusion related reaction
  2. Arthritis (form of joint disorder that involves inflammation of one or more joints)
  3. Arthropathy
  4. Cartilage atrophy (cartilage extra growth)
  5. Ear pain
  6. Fatigue (feeling of tiredness)
  7. Hypersensitivity
  8. Intervertebral disc protrusion (spinal disc protrusion)
  9. Malaise (a feeling of general discomfort or uneasiness)
  10. Memory impairment

50-59:

  1. Abdominal pain
  2. Blood magnesium decreased
  3. Colitis ulcerative (inflammation of colon with ulcer)
  4. Cyst (a closed sac)
  5. Frequent bowel movements
  6. Haemoglobin decreased
  7. Increased tendency to bruise (increased tendency to injure the underlying soft tissue or bone)
  8. Irritable bowel syndrome
  9. Nausea (feeling of having an urge to vomit)
  10. Platelet count decreased

60+:

  1. Urinary tract infection
  2. Death
  3. Drug hypersensitivity
  4. Endocarditis (inflammation in heart muscle)
  5. Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
  6. Neoplasm progression (growth of tumour)
  7. Rehabilitation therapy
  8. Sepsis (a severe blood infection that can lead to organ failure and death)
  9. Septic shock (shock due to blood infection)

What are the existing conditions these people have? *

  1. Intervertebral Disc Protrusion (spinal disc protrusion): 10 people, 45.45%
  2. Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 10 people, 45.45%
  3. Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 7 people, 31.82%
  4. Pain: 5 people, 22.73%
  5. Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 3 people, 13.64%
  6. Arthritis (form of joint disorder that involves inflammation of one or more joints): 2 people, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Cannabis and Vesicare?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Cannabis and Vesicare:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Cannabis:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Vesicare:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Cannabis and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Vesicare and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on marijuana and solifenacin succinate (the active ingredients of Cannabis and Vesicare, respectively), and Cannabis and Vesicare (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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