Capoten and Pantoprazole drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Capoten (captopril) and Pantoprazole (pantoprazole sodium). Common drug interactions include blood triglycerides increased among females and acute respiratory failure among males.

The phase IV clinical study analyzes what interactions people have when they take Capoten and Pantoprazole. It is created by eHealthMe based on reports of 20 people who take the same drugs from the FDA, and is updated regularly.

What is Capoten?

Capoten has active ingredients of captopril. It is often used in high blood pressure. eHealthMe is studying from 2,954 Capoten users. Check the latest studies of Capoten.

What is Pantoprazole?

Pantoprazole has active ingredients of pantoprazole sodium. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 285,165 Pantoprazole users. Check the latest studies of Pantoprazole.



On Jul, 10, 2026

20 people who take Capoten and Pantoprazole together, and have interactions are studied.

Capoten and Pantoprazole drug interactions.

What are the common drug interactions of Capoten and Pantoprazole, by gender? *:

female:

  1. Blood triglycerides increased
  2. Blood uric acid increased
  3. Brain natriuretic peptide increased
  4. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  5. Cardiac failure congestive
  6. Cardioactive drug level below therapeutic
  7. Cardiomyopathy (weakening of the heart muscle)
  8. Cellulitis (infection under the skin)
  9. Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
  10. Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)

male:

  1. Acute respiratory failure
  2. Bradycardia (abnormally slow heart action)
  3. Anaemia (lack of blood)
  4. Arthralgia (joint pain)
  5. Cardiac failure congestive
  6. Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection)
  7. Enterococcal infection
  8. Haemorrhage (bleeding)
  9. Hyperkalaemia (damage to or disease of the kidney)
  10. Ischaemic cardiomyopathy (weakness in the muscle of the heart due to inadequate oxygen delivery to the myocardium with coronary artery disease)

What are the common drug interactions of Capoten and Pantoprazole, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

  1. Bradycardia (abnormally slow heart action)
  2. Malaise (a feeling of general discomfort or uneasiness)

10-19:

n/a

20-29:

n/a

30-39:

  1. Arthralgia (joint pain)
  2. Joint stiffness
  3. Mobility decreased (ability to move is reduced)
  4. Myalgia (muscle pain)
  5. Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)
  6. Oedema peripheral (superficial swelling)
  7. Pain in extremity

40-49:

n/a

50-59:

  1. Dehydration (dryness resulting from the removal of water)
  2. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  3. Dyslipidaemia (abnormal amount of lipids)
  4. Epistaxis (bleed from the nose)
  5. Gout (uric acid crystals building up in the body)
  6. Hypokalaemia (low potassium)
  7. Intermittent claudication
  8. International normalised ratio increased
  9. Rectal haemorrhage (bleeding from anus)
  10. Renal cyst (kidney cyst)

60+:

  1. Pneumonia
  2. Sepsis (a severe blood infection that can lead to organ failure and death)
  3. Thrombocytopenia (decrease of platelets in blood)
  4. Abdominal wall haematoma (abdominal wall blood clotting)
  5. Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection)
  6. Confusional state
  7. Decubitus ulcer (a chronic ulcer of the skin caused by prolonged pressure on it)
  8. Encephalopathy (functioning of the brain is affected by some agent or condition)
  9. Enterococcal infection
  10. Haemorrhage (bleeding)

What are the existing conditions these people have? *

  1. High Blood Cholesterol: 4 people, 20.00%
  2. Oedema (fluid collection in tissue): 3 people, 15.00%
  3. Kidney Stones: 3 people, 15.00%
  4. Infection: 3 people, 15.00%
  5. Gastrointestinal Disorder (functional problems of gastrointestinal tract): 2 people, 10.00%
  6. Chronic Allograft Nephropathy (failure of kidney transplant): 1 person, 5.00%
  7. Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 1 person, 5.00%
  8. Depression: 1 person, 5.00%
  9. Diabetes: 1 person, 5.00%
  10. Drug Administration Error: 1 person, 5.00%

* Approximation only. Some reports may have incomplete information.

Do you take Capoten and Pantoprazole?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Capoten and Pantoprazole:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Capoten:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Pantoprazole:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Capoten and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Pantoprazole and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on captopril and pantoprazole sodium (the active ingredients of Capoten and Pantoprazole, respectively), and Capoten and Pantoprazole (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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