Captopril and Arthrotec drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Captopril (captopril) and Arthrotec (diclofenac sodium; misoprostol). Common drug interactions include appetite decreased among females and dizziness among males.

The phase IV clinical study analyzes what interactions people have when they take Captopril and Arthrotec. It is created by eHealthMe based on reports of 15 people who take the same drugs from the FDA, and is updated regularly.

What is Captopril?

Captopril has active ingredients of captopril. It is often used in high blood pressure. eHealthMe is studying from 17,438 Captopril users. Check the latest studies of Captopril.

What is Arthrotec?

Arthrotec has active ingredients of diclofenac sodium; misoprostol. It is often used in arthritis. eHealthMe is studying from 11,986 Arthrotec users. Check the latest studies of Arthrotec.



On Jul, 27, 2026

15 people who take Captopril and Arthrotec together, and have interactions are studied.

Captopril and Arthrotec drug interactions.

What are the common drug interactions of Captopril and Arthrotec, by gender? *:

female:

  1. Appetite decreased (decreased appetite occurs when you have a reduced desire to eat)
  2. Asthma
  3. Diarrhoea
  4. Diffuse alveolar damage (common manifestation of drug-induced lung injury)
  5. Dyspnoea (difficult or laboured respiration)
  6. Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
  7. Ill-defined disorder
  8. Interstitial lung disease
  9. Multi-organ failure (multisystem organ failure)
  10. Muscle necrosis (muscle cell damage)

male:

  1. Dizziness
  2. Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
  3. Hypokalaemia (low potassium)
  4. Injury
  5. Irritable bowel syndrome
  6. Nephrolithiasis (calculi in the kidneys)
  7. Oedema peripheral (superficial swelling)
  8. Orthostatic hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up)
  9. Vertigo
  10. Intervertebral disc protrusion (spinal disc protrusion)

What are the common drug interactions of Captopril and Arthrotec, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Abdominal distension
  2. Anxiety
  3. Back pain
  4. Cardiomyopathy (weakening of the heart muscle)
  5. Obesity (having too much body fat)
  6. Pulmonary oedema (fluid accumulation in the lungs)
  7. Abdominal pain
  8. Anaemia (lack of blood)
  9. Arteriosclerosis (thickening and hardening of arteries)
  10. Arthralgia (joint pain)

50-59:

  1. Asthma
  2. Oedema peripheral (superficial swelling)

60+:

  1. Buttock pain
  2. Dizziness
  3. Intervertebral disc protrusion (spinal disc protrusion)
  4. Radiculopathy (a set of conditions in which one or more nerves is affected and does not work properly)
  5. Acute myocardial infarction (acute heart attack)
  6. Appetite decreased (decreased appetite occurs when you have a reduced desire to eat)
  7. Cardiac failure congestive
  8. Diarrhoea
  9. Diffuse alveolar damage (common manifestation of drug-induced lung injury)
  10. Dyspnoea (difficult or laboured respiration)

What are the existing conditions these people have? *

  1. Gastric Disorder (disease of stomach): 3 people, 20.00%
  2. Sciatic Nerve Neuropathy (sciatic nerve damage): 2 people, 13.33%
  3. Hyperlipidaemia (presence of excess lipids in the blood): 2 people, 13.33%
  4. Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 1 person, 6.67%
  5. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 6.67%
  6. Pain: 1 person, 6.67%
  7. Irritable Bowel Syndrome: 1 person, 6.67%
  8. High Blood Cholesterol: 1 person, 6.67%
  9. Diabetes: 1 person, 6.67%
  10. Blockage Of Leg Arteries: 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Captopril and Arthrotec?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Captopril and Arthrotec:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Captopril:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Arthrotec:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Captopril and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Arthrotec and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on captopril and diclofenac sodium; misoprostol (the active ingredients of Captopril and Arthrotec, respectively), and Captopril and Arthrotec (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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