Repaglinide and Cephalexin drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Repaglinide (repaglinide) and Cephalexin (cephalexin). Common drug interactions include chronic kidney disease among females and anaemia among males.
The phase IV clinical study analyzes what interactions people have when they take Repaglinide and Cephalexin. It is created by eHealthMe based on reports of 26 people who take the same drugs from the FDA, and is updated regularly.
What is Repaglinide?
Repaglinide has active ingredients of repaglinide. It is often used in diabetes. eHealthMe is studying from 8,226 Repaglinide users. Check the latest studies of Repaglinide.
What is Cephalexin?
Cephalexin has active ingredients of cephalexin. It is often used in infection. eHealthMe is studying from 30,580 Cephalexin users. Check the latest studies of Cephalexin.
26 people who take Repaglinide and Cephalexin together, and have interactions are studied.

What are the common drug interactions of Repaglinide and Cephalexin, by gender? *:
female:
- Chronic kidney disease
- Renal failure (kidney dysfunction)
- Renal injury (kidney injury)
- Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
- Nephrogenic anaemia (anaemia due to kidney disease)
- Dyspepsia (indigestion)
- Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
- Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
- Cardiac failure congestive
- Death
male:
- Anaemia (lack of blood)
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection)
- Death
- Decreased appetite
- Weight decreased
- Anxiety
- Chronic kidney disease
- Emotional distress
- Gout (uric acid crystals building up in the body)
What are the common drug interactions of Repaglinide and Cephalexin, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Epigastric discomfort
- Gastritis (inflammation of stomach)
- Acute respiratory distress syndrome
- Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
- Cardiac failure congestive
- Chronic kidney disease
- Coma (state of unconsciousness lasting more than six hours)
- Drug clearance decreased
- Feeding disorder (when children refuse to eat certain food groups)
- Nasopharyngitis (inflammation of the nasopharynx)
50-59:
- Chronic kidney disease
- Renal failure (kidney dysfunction)
- Renal injury (kidney injury)
- Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
- Death
- Dyspepsia (indigestion)
- Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
- Nephrogenic anaemia (anaemia due to kidney disease)
- Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
- Hyperkalaemia (damage to or disease of the kidney)
60+:
- Anaemia (lack of blood)
- Chronic kidney disease
- Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
- Atrioventricular block first degree (heart block first degree)
- Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection)
- Fatigue (feeling of tiredness)
- Folliculitis (infection of hair root)
- Haemoglobin decreased
- Loss of consciousness
- Macroangiopathy (a disease of the large blood vessels in which fat and blood clots build up and stick to the vessel walls, blocking the flow of blood)
What are the existing conditions these people have? *
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 8 people, 30.77%
- Nausea (feeling of having an urge to vomit): 3 people, 11.54%
- High Blood Cholesterol: 3 people, 11.54%
- Depression: 3 people, 11.54%
- Constipation: 3 people, 11.54%
- Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 7.69%
- Pain: 2 people, 7.69%
- Multiple Myeloma (cancer of the plasma cells): 2 people, 7.69%
- Ill-Defined Disorder: 2 people, 7.69%
- Hiv Infection: 2 people, 7.69%
* Approximation only. Some reports may have incomplete information.
Do you take Repaglinide and Cephalexin?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Repaglinide (8,226 reports)
- Cephalexin (30,580 reports)
Browse all drug interactions of Repaglinide and Cephalexin:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Repaglinide:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Cephalexin:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Repaglinide and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Cephalexin and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Agrawal A, Rao M, Jasdanwala S, Mathur A, Eng M, "Cephalexin Induced Cholestatic Jaundice", Case reports in gastrointestinal medicine, 2014 Aug .
- Agrawal A, Rao M, Jasdanwala S, Mathur A, Eng M, "Cephalexin Induced Cholestatic Jaundice", Case reports in gastrointestinal medicine, 2014 Aug .
How the study uses the data?
The study uses data from the FDA. It is based on repaglinide and cephalexin (the active ingredients of Repaglinide and Cephalexin, respectively), and Repaglinide and Cephalexin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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