Cardene and Avapro drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Cardene (nicardipine hydrochloride) and Avapro (irbesartan). Common drug interactions include depression among females and acute respiratory distress syndrome among males.

The phase IV clinical study analyzes what interactions people have when they take Cardene and Avapro. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.

What is Cardene?

Cardene has active ingredients of nicardipine hydrochloride. eHealthMe is studying from 729 Cardene users. Check the latest studies of Cardene.

What is Avapro?

Avapro has active ingredients of irbesartan. It is often used in high blood pressure. eHealthMe is studying from 19,840 Avapro users. Check the latest studies of Avapro.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 03, 2026

14 people who take Cardene and Avapro together, and have interactions are studied.

What are the common drug interactions of Cardene and Avapro, by gender? *:

female:

Depression
Fear
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
Ileus (a painful obstruction of the ileum or other part of the intestine)
Injury
Multi-organ failure (multisystem organ failure)
Nephrogenic anaemia (anaemia due to kidney disease)
Pain
Renal failure (kidney dysfunction)
Renal failure acute (rapid kidney dysfunction)

male:

Acute respiratory distress syndrome
Atrioventricular block first degree (heart block first degree)
Osteoarthritis (a joint disease caused by cartilage loss in a joint)
Renal failure acute (rapid kidney dysfunction)
Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down)
Rheumatoid factor positive
Skin discolouration (change of skin colour)
Cough
Inappropriate antidiuretic hormone secretion
Choking sensation (feeling of obstruction in respiratory system)

What are the common drug interactions of Cardene and Avapro, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
Ileus (a painful obstruction of the ileum or other part of the intestine)
Injury
Multi-organ failure (multisystem organ failure)
Nephrogenic anaemia (anaemia due to kidney disease)
Pain
Renal failure (kidney dysfunction)
Renal failure acute (rapid kidney dysfunction)
Renal impairment (severely reduced kidney function)
Renal injury (kidney injury)

60+:

Acute respiratory distress syndrome
Atrioventricular block first degree (heart block first degree)
Osteoarthritis (a joint disease caused by cartilage loss in a joint)
Renal failure acute (rapid kidney dysfunction)
Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down)
Rheumatoid factor positive
Skin discolouration (change of skin colour)
Cough
Inappropriate antidiuretic hormone secretion
Choking sensation (feeling of obstruction in respiratory system)

What are the existing conditions these people have? *

Type 2 Diabetes: 2 people, 14.29%
Diabetes: 2 people, 14.29%
Cardiac Disorder: 2 people, 14.29%
Intervertebral Disc Degeneration (spinal disc degeneration): 1 person, 7.14%
Hypersensitivity: 1 person, 7.14%
High Blood Cholesterol: 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Cardene and Avapro?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously