Cardizem cd and Vytorin drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Cardizem cd (diltiazem hydrochloride) and Vytorin (ezetimibe; simvastatin). Common drug interactions include left ventricular hypertrophy among females and drug ineffective among males.
The phase IV clinical study analyzes what interactions people have when they take Cardizem cd and Vytorin. It is created by eHealthMe based on reports of 42 people who take the same drugs from the FDA, and is updated regularly.
What is Cardizem cd?
Cardizem cd has active ingredients of diltiazem hydrochloride. It is often used in high blood pressure. eHealthMe is studying from 6,045 Cardizem cd users. Check the latest studies of Cardizem cd.
What is Vytorin?
Vytorin has active ingredients of ezetimibe; simvastatin. It is often used in high blood cholesterol. eHealthMe is studying from 20,084 Vytorin users. Check the latest studies of Vytorin.
42 people who take Cardizem cd and Vytorin together, and have interactions are studied.

What are the common drug interactions of Cardizem Cd and Vytorin, by gender? *:
female:
- Left ventricular hypertrophy (the thickening of the myocardium (muscle) of the left ventricle of the heart)
- Memory impairment
- Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
- Mesenteric artery stenosis (narrowing of the arteries supplying blood to the intestines)
- Multiple injuries
- Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
- Neuropathy peripheral (surface nerve damage)
- Orthostatic hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up)
- Osteoarthritis (a joint disease caused by cartilage loss in a joint)
- Pain
male:
- Drug ineffective
- Dry mouth
- Palatal disorder
- Pharyngeal neoplasm (pharyngeal tumour)
- Abasia (inability to walk)
- Acute myocardial infarction (acute heart attack)
- Arthralgia (joint pain)
- Asthenopia (eyestrain-tiredness of the eyes caused by prolonged close work by a person with an uncorrected vision problem)
- Atrial tachycardia (rhythm disturbance that arises in the atria)
- Bladder cancer
What are the common drug interactions of Cardizem Cd and Vytorin, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Diabetic coma
- Diabetic foot
- Diarrhoea
- Electrocardiogram qt prolonged
- Hypokalaemia (low potassium)
- Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood)
- Neuropathy peripheral (surface nerve damage)
- Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
- Polyneuropathy (neurological disorder that occurs when many peripheral nerves throughout the body malfunction simultaneously)
- Polyneuropathy idiopathic progressive (progressive disorder that affects the peripheral nerves and has no identifiable primary cause)
50-59:
- Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
- Malignant melanoma (skin cancer rises from melancytes)
- Abnormal dreams
- Acute myocardial infarction (acute heart attack)
- Adverse event
- Alcohol poisoning
- Alcohol problem
- Anxiety
- Asthenopia (eyestrain-tiredness of the eyes caused by prolonged close work by a person with an uncorrected vision problem)
- Bladder cancer
60+:
- Haematuria (presence of blood in urine)
- Dry mouth
- Abdominal discomfort
- Abdominal pain upper
- Arthralgia (joint pain)
- Ascites (accumulation of fluid in the abdominal cavity)
- Atrial tachycardia (rhythm disturbance that arises in the atria)
- Balance disorder
- Biliary dilatation
- Blood creatine phosphokinase increased
What are the existing conditions these people have? *
- Diabetes: 10 people, 23.81%
- Type 2 Diabetes: 4 people, 9.52%
- Neuralgia (pain in one or more nerves): 4 people, 9.52%
- Peripheral Neuropathy (damage to nerves of the peripheral nervous system): 3 people, 7.14%
- Fluid Retention (an abnormal accumulation of fluid in the blood): 3 people, 7.14%
- Depression: 3 people, 7.14%
- Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 3 people, 7.14%
* Approximation only. Some reports may have incomplete information.
Do you take Cardizem cd and Vytorin?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Cardizem cd (6,045 reports)
- Vytorin (20,084 reports)
Browse all drug interactions of Cardizem cd and Vytorin:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Cardizem cd:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Vytorin:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Cardizem cd and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Vytorin and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on diltiazem hydrochloride and ezetimibe; simvastatin (the active ingredients of Cardizem cd and Vytorin, respectively), and Cardizem cd and Vytorin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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