Cardizem and Persantine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Cardizem (diltiazem hydrochloride) and Persantine (dipyridamole). Common drug interactions include anaemia among females and ecchymosis among males.

The phase IV clinical study analyzes what interactions people have when they take Cardizem and Persantine. It is created by eHealthMe based on reports of 60 people who take the same drugs from the FDA, and is updated regularly.

What is Cardizem?

Cardizem has active ingredients of diltiazem hydrochloride. It is often used in high blood pressure. eHealthMe is studying from 28,014 Cardizem users. Check the latest studies of Cardizem.

What is Persantine?

Persantine has active ingredients of dipyridamole. eHealthMe is studying from 2,427 Persantine users. Check the latest studies of Persantine.

On Jul, 14, 2026

60 people who take Cardizem and Persantine together, and have interactions are studied.

Cardizem and Persantine drug interactions.

What are the common drug interactions of Cardizem and Persantine, by gender? *:

female:

Anaemia (lack of blood)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Headache (pain in head)
Oedema peripheral (superficial swelling)
Progressive multifocal leukoencephalopathy (rapidly progressive neuromuscular disease caused by opportunistic infection of brain cells)
Urinary tract infection
Ventricular extrasystoles (premature cardiac contraction)
Ventricular tachycardia (rapid heartbeat that originates in one of the lower chambers (the ventricles) of the heart)
Vomiting
Chest discomfort

male:

Ecchymosis (a discoloration of the skin resulting from bleeding underneath)
Hypotension (abnormally low blood pressure)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Pyrexia (fever)
Renal impairment (severely reduced kidney function)
Agitation (state of anxiety or nervous excitement)
Ammonia increased
Anaemia (lack of blood)
Angina unstable (chest pain due to ischemia of the heart muscle- unstable)
Angioneurotic oedema (swelling that occurs just beneath the surface of the skin or mucous membranes)

What are the common drug interactions of Cardizem and Persantine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Anaemia (lack of blood)
Breast disorder male
Cardiac failure congestive
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Constipation
Ecchymosis (a discoloration of the skin resulting from bleeding underneath)
Hiatus hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm)
Induration (thickening of tissue)
Oesophageal ulcer (ulcer of oesophagus)
Oesophagitis (inflammation of oesophagus)

30-39:

n/a

40-49:

Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)
Atrioventricular block complete (heart block complete)
Bradycardia (abnormally slow heart action)
Epigastric discomfort
Hypotension (abnormally low blood pressure)
Presyncope
Ventricular tachycardia (rapid heartbeat that originates in one of the lower chambers (the ventricles) of the heart)

50-59:

Seizure (abnormal excessive or synchronous neuronal activity in the brain)
Urticaria (rash of round, red welts on the skin that itch intensely)
Vasodilatation (widening of blood vessels resulting from relaxation of smooth muscle cells within the vessel walls)
Progressive multifocal leukoencephalopathy (rapidly progressive neuromuscular disease caused by opportunistic infection of brain cells)
Chest discomfort
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Bradycardia (abnormally slow heart action)
Drug ineffective
Dysphagia (a condition in which swallowing is difficult or painful)
Gamma-glutamyltransferase increased

60+:

Depression
Dyspnoea (difficult or laboured respiration)
Death
Emotional distress
Fear
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Hypotension (abnormally low blood pressure)
Injury
International normalised ratio decreased
Nausea (feeling of having an urge to vomit)

What are the existing conditions these people have? *

Heart Attack: 4 people, 6.67%
Acute Myocardial Infarction (acute heart attack): 4 people, 6.67%
Diarrhea: 3 people, 5.00%

* Approximation only. Some reports may have incomplete information.

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