Carvedilol and Orphenadrine citrate drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Carvedilol (carvedilol) and Orphenadrine citrate (orphenadrine citrate). Common drug interactions include chronic kidney disease among females and nausea among males.

The phase IV clinical study analyzes what interactions people have when they take Carvedilol and Orphenadrine citrate. It is created by eHealthMe based on reports of 30 people who take the same drugs from the FDA, and is updated regularly.

What is Carvedilol?

Carvedilol has active ingredients of carvedilol. It is often used in high blood pressure. eHealthMe is studying from 112,649 Carvedilol users. Check the latest studies of Carvedilol.

What is Orphenadrine citrate?

Orphenadrine citrate has active ingredients of orphenadrine citrate. It is often used in muscle aches. eHealthMe is studying from 1,189 Orphenadrine citrate users. Check the latest studies of Orphenadrine citrate.

On Jul, 15, 2026

30 people who take Carvedilol and Orphenadrine citrate together, and have interactions are studied.

Carvedilol and Orphenadrine citrate drug interactions.

What are the common drug interactions of Carvedilol and Orphenadrine Citrate, by gender? *:

female:

Chronic kidney disease
Renal failure (kidney dysfunction)
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Nephrogenic anaemia (anaemia due to kidney disease)
Tubo-ovarian abscess (an abscess that involves the fallopian tube and corresponding ovary that is usually associated with inflammation of the fallopian tube)
Chest pain
Malaise (a feeling of general discomfort or uneasiness)
Overdose
Seizure (abnormal excessive or synchronous neuronal activity in the brain)
Anxiety

male:

Nausea (feeling of having an urge to vomit)
Anxiety
Drug dependence
Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
Eating disorder
Hypokalaemia (low potassium)
Impaired driving ability
Lethargy (tiredness)
Loss of consciousness
Lumbar spinal stenosis (a medical condition in which the spinal canal narrows and compresses the spinal cord and nerves at the level of the lumbar bone)

What are the common drug interactions of Carvedilol and Orphenadrine Citrate, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Chronic kidney disease
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)

40-49:

Chronic kidney disease
Renal failure (kidney dysfunction)
Renal impairment (severely reduced kidney function)
Renal tubular necrosis (death of kidney tubules)

50-59:

Anxiety
Fatigue (feeling of tiredness)
Productive cough
Weight decreased
Chest pain
Erythema (redness of the skin)
Overdose
Seizure (abnormal excessive or synchronous neuronal activity in the brain)
Syncope (loss of consciousness with an inability to maintain postural tone)
Cardiac failure congestive

60+:

Chronic kidney disease
Renal failure (kidney dysfunction)
Death
Fall
Fatigue (feeling of tiredness)
Gout (uric acid crystals building up in the body)
Hand fracture
Lumbar vertebral fracture
Nodule (a growth of abnormal tissue)
Oesophageal stenosis (narrowing of oesophagus)

What are the existing conditions these people have? *

Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 13 people, 43.33%
High Blood Cholesterol: 11 people, 36.67%
Pain: 10 people, 33.33%
Infection: 9 people, 30.00%
Stress And Anxiety: 8 people, 26.67%
Neuralgia (pain in one or more nerves): 7 people, 23.33%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 6 people, 20.00%
Muscle Spasms (muscle contraction): 5 people, 16.67%
Diabetes: 5 people, 16.67%
Hypersensitivity: 5 people, 16.67%

* Approximation only. Some reports may have incomplete information.

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