Carvedilol and Perphenazine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Carvedilol (carvedilol) and Perphenazine (perphenazine). Common drug interactions include chronic kidney disease among females and angina pectoris among males.

The phase IV clinical study analyzes what interactions people have when they take Carvedilol and Perphenazine. It is created by eHealthMe based on reports of 28 people who take the same drugs from the FDA, and is updated regularly.

What is Carvedilol?

Carvedilol has active ingredients of carvedilol. It is often used in high blood pressure. eHealthMe is studying from 112,649 Carvedilol users. Check the latest studies of Carvedilol.

What is Perphenazine?

Perphenazine has active ingredients of perphenazine. It is often used in bipolar i disorder. eHealthMe is studying from 2,712 Perphenazine users. Check the latest studies of Perphenazine.

On Jul, 15, 2026

28 people who take Carvedilol and Perphenazine together, and have interactions are studied.

Carvedilol and Perphenazine drug interactions.

What are the common drug interactions of Carvedilol and Perphenazine, by gender? *:

female:

Chronic kidney disease
Pancreatic cyst
Pancreatitis acute (sudden inflammation of pancreas)
Death
Genital prolapse (portion of the vaginal canal protruding (prolapsing) from the opening of the vagina)
Insomnia (sleeplessness)
Quality of life decreased
Salivary hypersecretion (excess saliva secretion)
Speech disorder
Anhedonia (inability to experience pleasure from activities usually found enjoyable)

male:

Angina pectoris (chest pain due to ischemia of the heart muscle)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Renal injury (kidney injury)
Death
Haemorrhage urinary tract (bleeding from uterine)
Nephrogenic anaemia (anaemia due to kidney disease)
Pain in extremity
Renal artery stenosis (narrowing of renal artery)
Renal failure (kidney dysfunction)
Renal tubular necrosis (death of kidney tubules)

What are the common drug interactions of Carvedilol and Perphenazine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Bone density decreased
Chronic kidney disease
Death
Depression
Emotional distress
Pain
Renal injury (kidney injury)

50-59:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Decreased activity
Depression
Emotional distress
Fatigue (feeling of tiredness)
Pain
Quality of life decreased
Dry skin
Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters)

60+:

Chronic kidney disease
Pancreatic cyst
Cardiac arrest
Cardiac failure congestive
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Fall
Nephrogenic anaemia (anaemia due to kidney disease)
Renal failure (kidney dysfunction)
Respiratory failure (inadequate gas exchange by the respiratory system)
Pancreatitis acute (sudden inflammation of pancreas)

What are the existing conditions these people have? *

Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 21.43%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 5 people, 17.86%
Type 2 Diabetes: 3 people, 10.71%
Hiv Infection: 3 people, 10.71%
Stress And Anxiety: 2 people, 7.14%
Rashes (redness): 2 people, 7.14%
Pain: 2 people, 7.14%
Hypocalcaemia (levels of calcium in blood serum are abnormally low): 2 people, 7.14%
Hyperlipidaemia (presence of excess lipids in the blood): 2 people, 7.14%
High Blood Cholesterol: 2 people, 7.14%

* Approximation only. Some reports may have incomplete information.

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