Carvedilol and Vfend drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Carvedilol (carvedilol) and Vfend (voriconazole). Common drug interactions include pneumonia pseudomonal among females and pneumonia among males.
The phase IV clinical study analyzes what interactions people have when they take Carvedilol and Vfend. It is created by eHealthMe based on reports of 70 people who take the same drugs from the FDA, and is updated regularly.
What is Carvedilol?
Carvedilol has active ingredients of carvedilol. It is often used in high blood pressure. eHealthMe is studying from 112,649 Carvedilol users. Check the latest studies of Carvedilol.
What is Vfend?
Vfend has active ingredients of voriconazole. It is often used in aspergillosis. eHealthMe is studying from 12,128 Vfend users. Check the latest studies of Vfend.
70 people who take Carvedilol and Vfend together, and have interactions are studied.

What are the common drug interactions of Carvedilol and Vfend, by gender? *:
female:
- Pneumonia pseudomonal (pseudomonas pneumonia is an infection caused by the microbe known as pseudomonas aeruginosa)
- Visual impairment
- Photophobia (extreme sensitivity to light)
- Spinal fracture (fracture in one of vertebrae)
- Acute myeloid leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts)
- Adverse event
- Blood glucose increased
- Bone marrow failure
- Chest pain
- Dehydration (dryness resulting from the removal of water)
male:
- Pneumonia
- Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
- Blood creatinine increased
- Pseudoporphyria (skin changes consistent with one of the porphyrias, but laboratory tests do not detect significant abnormalities)
- Bronchopulmonary aspergillosis (lung disorder caused by aspergillus fungi)
- Diarrhoea
- Disorientation (disability in which the senses of time, direction, and recognition of people and places)
- Dizziness
- Hallucination (an experience involving the perception of something not present)
- Interstitial lung disease
What are the common drug interactions of Carvedilol and Vfend, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Blood creatine phosphokinase increased
- Engraftment syndrome (inflammatory condition during neutrophil recovery after hematopoietic stem cell transplantation)
- Myositis (inflammation of the muscles)
- Pain
30-39:
n/a
40-49:
- Gamma-glutamyltransferase increased
- Liver disorder (liver diseases)
- Biliary tract disorder
- Cholestasis (a condition where bile cannot flow from the liver to the duodenum)
- Dehydration (dryness resulting from the removal of water)
- Disease complication
- Graft versus host disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body)
- Lymphoma (cancer that begins in immune system cells)
- Neutropenia (an abnormally low number of neutrophils)
- Renal disorder (kidney disease)
50-59:
- Acute myeloid leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts)
- Anaemia (lack of blood)
- Arrhythmia (irregular heartbeat)
- Arthralgia (joint pain)
- Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
- Blood creatinine increased
- Bone marrow failure
- Cardiac enzymes increased
- Diarrhoea
- Dysgeusia (disorder of the sense of taste)
60+:
- Pneumonia
- Abdominal pain upper
- Memory impairment
- Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
- Skin exfoliation (removal of the oldest dead skin cells)
- Stomatitis (inflammation of mucous membrane of mouth)
- Weight decreased
- Hallucination (an experience involving the perception of something not present)
- Abdominal discomfort
- Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
What are the existing conditions these people have? *
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 12 people, 17.14%
- Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 9 people, 12.86%
- Cardiac Disorder: 8 people, 11.43%
- Diabetes: 7 people, 10.00%
- Pain: 6 people, 8.57%
- Stress And Anxiety: 5 people, 7.14%
- Lung Infection: 5 people, 7.14%
- Nausea And Vomiting: 4 people, 5.71%
- Hypokalemia (low potassium): 4 people, 5.71%
- Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 4 people, 5.71%
* Approximation only. Some reports may have incomplete information.
Do you take Carvedilol and Vfend?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Carvedilol (112,649 reports)
- Vfend (12,128 reports)
Browse all drug interactions of Carvedilol and Vfend:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Carvedilol:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Vfend:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Carvedilol and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Vfend and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Barold, S. S., & Upton, S. , "Hyperkalemia Induced by the Sequential Administration of Metoprolol and Carvedilol", Case reports in cardiology, 2018 Jan .
- Kim MS, Baek IH, "Effect of dronedarone on the pharmacokinetics of carvedilol following oral administration to rats", European Journal of Pharmaceutical Sciences, 2018 Jan .
- Barold, S. S., & Upton, S. , "Hyperkalemia Induced by the Sequential Administration of Metoprolol and Carvedilol", Case reports in cardiology, 2018 Jan .
- Kim MS, Baek IH, "Effect of dronedarone on the pharmacokinetics of carvedilol following oral administration to rats", European Journal of Pharmaceutical Sciences, 2018 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on carvedilol and voriconazole (the active ingredients of Carvedilol and Vfend, respectively), and Carvedilol and Vfend (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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