Carvedilol and Zelnorm drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Carvedilol (carvedilol) and Zelnorm (tegaserod maleate). Common drug interactions include abdominal pain upper among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Carvedilol and Zelnorm. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.

What is Carvedilol?

Carvedilol has active ingredients of carvedilol. It is often used in high blood pressure. eHealthMe is studying from 112,649 Carvedilol users. Check the latest studies of Carvedilol.

What is Zelnorm?

Zelnorm has active ingredients of tegaserod maleate. eHealthMe is studying from 7,261 Zelnorm users. Check the latest studies of Zelnorm.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 27, 2026

16 people who take Carvedilol and Zelnorm together, and have interactions are studied.

Carvedilol and Zelnorm drug interactions.

What are the common drug interactions of Carvedilol and Zelnorm, by gender? *:

female:

Abdominal pain upper
Abdominal tenderness
Amylase increased
Anaemia (lack of blood)
Anxiety
Asthenia (weakness)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Back pain
Blood creatine phosphokinase increased
Bradycardia (abnormally slow heart action)

male:

Chronic kidney disease
Renal failure (kidney dysfunction)
Aortic aneurysm (enlargement of an aortic artery caused by a weakening of the artery wall)
Arthralgia (joint pain)
Atrioventricular block complete (heart block complete)
Azotaemia (excess of urea or other nitrogenous compounds in the blood)
Balance disorder
Benign prostatic hyperplasia (benign enlargement of the prostate)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Cardiac arrest

What are the common drug interactions of Carvedilol and Zelnorm, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Anxiety
Dizziness
Malabsorption (a state arising from abnormality in absorption of food nutrients across the gastrointestinal (gi) tract)
Rectal haemorrhage (bleeding from anus)

50-59:

Angina pectoris (chest pain due to ischemia of the heart muscle)
Blood creatine phosphokinase increased
Bundle branch block left (absence of transmission of electric impulses from the atrioventricular (av) bundle of his to the left ventricle)
Dyspnoea (difficult or laboured respiration)
Left ventricular dysfunction
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Myocarditis (inflammation of heart muscle myocardium)
Myopathy (a muscular disease in which the muscle fibres do not function)
Troponin increased
Chronic kidney disease

60+:

Chronic kidney disease
Renal cyst (kidney cyst)
Aortic aneurysm (enlargement of an aortic artery caused by a weakening of the artery wall)
Arthralgia (joint pain)
Asthenia (weakness)
Atrioventricular block complete (heart block complete)
Azotaemia (excess of urea or other nitrogenous compounds in the blood)
Balance disorder
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Cardiac arrest

What are the existing conditions these people have? *

Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 8 people, 50.00%
High Blood Cholesterol: 6 people, 37.50%
Pain: 5 people, 31.25%
Type 2 Diabetes: 3 people, 18.75%
Hypersensitivity: 3 people, 18.75%
Hyposmia (impairment of the sense of smell): 2 people, 12.50%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 2 people, 12.50%
Blood Pressure Abnormal: 2 people, 12.50%
Cardiac Failure Congestive: 2 people, 12.50%
Cataract (clouding of the lens inside the eye): 2 people, 12.50%

* Approximation only. Some reports may have incomplete information.

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