Cascara and Pantoprazole drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Cascara (cascara) and Pantoprazole (pantoprazole sodium). Common drug interactions include drug ineffective among females and constipation among males.

The phase IV clinical study analyzes what interactions people have when they take Cascara and Pantoprazole. It is created by eHealthMe based on reports of 31 people who take the same drugs from the FDA, and is updated regularly.

What is Cascara?

Cascara has active ingredients of cascara. eHealthMe is studying from 302 Cascara users. Check the latest studies of Cascara.

What is Pantoprazole?

Pantoprazole has active ingredients of pantoprazole sodium. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 285,165 Pantoprazole users. Check the latest studies of Pantoprazole.



On Jul, 20, 2026

31 people who take Cascara and Pantoprazole together, and have interactions are studied.

Cascara and Pantoprazole drug interactions.

What are the common drug interactions of Cascara and Pantoprazole, by gender? *:

female:

  1. Drug ineffective
  2. Dyspnoea (difficult or laboured respiration)
  3. Eosinophilia (eosinophil count in the peripheral blood exceeds)
  4. Lower respiratory tract infection
  5. Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
  6. Nausea (feeling of having an urge to vomit)
  7. Oedema peripheral (superficial swelling)
  8. Pneumonia viral
  9. Presyncope
  10. Productive cough

male:

  1. Constipation
  2. Intestinal obstruction
  3. Vomiting
  4. Drug effect decreased
  5. Post procedural complication
  6. Pulmonary embolism (blockage of the main artery of the lung)

What are the common drug interactions of Cascara and Pantoprazole, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Myoclonic epilepsy (type of epilepsy with quick little jerks of the arms, shoulder, or occasionally the legs)

50-59:

  1. Alopecia (absence of hair from areas of the body)
  2. Depression
  3. Dysstasia (difficulty in standing)
  4. Gait disturbance
  5. Hypoaesthesia (reduced sense of touch or sensation)
  6. Drug effect decreased
  7. Post procedural complication
  8. Pulmonary embolism (blockage of the main artery of the lung)

60+:

  1. Vomiting
  2. Pulmonary embolism (blockage of the main artery of the lung)
  3. Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
  4. Nausea (feeling of having an urge to vomit)
  5. Oedema peripheral (superficial swelling)
  6. Pneumonia viral
  7. Presyncope
  8. Productive cough
  9. Pyrexia (fever)
  10. Upper respiratory tract infection

What are the existing conditions these people have? *

  1. Asthma: 6 people, 19.35%
  2. Depression: 3 people, 9.68%
  3. Stomatitis (inflammation of mucous membrane of mouth): 2 people, 6.45%
  4. Glaucoma (increased fluid pressure in the eye with vision loss): 2 people, 6.45%
  5. Arthritis (form of joint disorder that involves inflammation of one or more joints): 2 people, 6.45%
  6. Bone Pain: 2 people, 6.45%
  7. Constipation: 2 people, 6.45%
  8. Dry Eyes (lack of adequate tears): 2 people, 6.45%
  9. Gait Disturbance: 2 people, 6.45%
  10. Gastric Disorder (disease of stomach): 2 people, 6.45%

* Approximation only. Some reports may have incomplete information.

Do you take Cascara and Pantoprazole?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Cascara and Pantoprazole:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Cascara:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Pantoprazole:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Cascara and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Pantoprazole and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on cascara and pantoprazole sodium (the active ingredients of Cascara and Pantoprazole, respectively), and Cascara and Pantoprazole (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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