Catapres and Xenical drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Catapres (clonidine hydrochloride) and Xenical (orlistat). Common drug interactions include diarrhoea among females and abdominal pain upper among males.

The phase IV clinical study analyzes what interactions people have when they take Catapres and Xenical. It is created by eHealthMe based on reports of 24 people who take the same drugs from the FDA, and is updated regularly.

What is Catapres?

Catapres has active ingredients of clonidine hydrochloride. It is often used in high blood pressure. eHealthMe is studying from 6,680 Catapres users. Check the latest studies of Catapres.

What is Xenical?

Xenical has active ingredients of orlistat. It is often used in weight loss. eHealthMe is studying from 11,722 Xenical users. Check the latest studies of Xenical.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 31, 2026

24 people who take Catapres and Xenical together, and have interactions are studied.

What are the common drug interactions of Catapres and Xenical, by gender? *:

female:

Diarrhoea
Constipation
Irritable bowel syndrome
Diabetes mellitus non insulin-dependent
Flatulence (flatus expelled through the anus)
Loose stools
Nausea (feeling of having an urge to vomit)
Blood in stool
Dehydration (dryness resulting from the removal of water)
Vomiting

male:

Abdominal pain upper
Chest pain
Asthenia (weakness)
Blood pressure fluctuation
Chronic kidney disease
Decreased activity
Emotional distress
Fatigue (feeling of tiredness)
Injury
Pain

What are the common drug interactions of Catapres and Xenical, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Abdominal pain upper
Chest pain
Death
Dyspnoea (difficult or laboured respiration)
Epigastric discomfort
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Stomach discomfort (pain in abdomen)
Vomiting
Injury
Abdominal pain

40-49:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Asthenia (weakness)
Back pain
Blood in stool
Blood pressure fluctuation
Chronic kidney disease
Constipation
Decreased activity
Emotional distress

50-59:

Diarrhoea
Anxiety
Blood glucose fluctuation
Blood in stool
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Colitis (inflammation of colon)
Communication disorder (speech and language disorder)
Crying
Defaecation urgency (a sudden compelling urge to defecate)
Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)

60+:

Diarrhoea
Irritable bowel syndrome
Pain
Renal disorder (kidney disease)
Spinal column stenosis (narrowing of spinal column)
Stress
Vomiting
Arthropathy
Blood creatine increased
Blood glucose increased

What are the existing conditions these people have? *

Pain: 3 people, 12.50%
Enlarged Heart: 3 people, 12.50%
Urinary Tract Infection: 2 people, 8.33%
Stress And Anxiety: 2 people, 8.33%
Joint Pain: 2 people, 8.33%
Hiv Infection: 2 people, 8.33%
High Blood Cholesterol: 2 people, 8.33%
Gastric Ulcer (stomach ulcer): 2 people, 8.33%
Diabetes: 2 people, 8.33%
Constipation: 2 people, 8.33%

* Approximation only. Some reports may have incomplete information.

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