Cefazolin sodium and Tylenol drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Cefazolin sodium (cefazolin sodium) and Tylenol (acetaminophen). Common drug interactions include anxiety among females and renal failure among males.

The phase IV clinical study analyzes what interactions people have when they take Cefazolin sodium and Tylenol. It is created by eHealthMe based on reports of 41 people who take the same drugs from the FDA, and is updated regularly.

What is Cefazolin sodium?

Cefazolin sodium has active ingredients of cefazolin sodium. eHealthMe is studying from 3,649 Cefazolin sodium users. Check the latest studies of Cefazolin sodium.

What is Tylenol?

Tylenol has active ingredients of acetaminophen. It is often used in pain. eHealthMe is studying from 222,309 Tylenol users. Check the latest studies of Tylenol.



On Jul, 17, 2026

41 people who take Cefazolin sodium and Tylenol together, and have interactions are studied.

Cefazolin sodium and Tylenol drug interactions.

What are the common drug interactions of Cefazolin Sodium and Tylenol, by gender? *:

female:

  1. Anxiety
  2. Back pain
  3. Depressed level of consciousness
  4. Red blood cell count decreased
  5. Staphylococcal infection (an infection with staphylococcus bacteria)
  6. Acute respiratory failure
  7. Blood pressure fluctuation
  8. Death
  9. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  10. Device related infection

male:

  1. Renal failure (kidney dysfunction)
  2. Hypotension (abnormally low blood pressure)
  3. Pleural effusion (water on the lungs)
  4. Restlessness (not able to rest)
  5. Type 2 diabetes mellitus
  6. Adrenal haemorrhage (bleeding into the adrenal gland)
  7. Cardiogenic shock (inadequate circulation of blood)
  8. Chronic kidney disease
  9. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  10. Dyspnoea (difficult or laboured respiration)

What are the common drug interactions of Cefazolin Sodium and Tylenol, by age (0-1 to 60+)? *:

0-1:

  1. Anxiety
  2. Atelectasis (partial or complete collapse of the lung)
  3. Blood chloride increased
  4. Cardiac failure
  5. Cold sweat
  6. Confusional state
  7. Feeling cold
  8. Fluid overload (too much fluid in the blood)
  9. Haematocrit decreased
  10. Haemoglobin decreased

2-9:

  1. Alanine aminotransferase increased
  2. Anaemia (lack of blood)
  3. Bone pain
  4. Constipation
  5. Febrile neutropenia (fever with reduced white blood cells)
  6. Hypotension (abnormally low blood pressure)
  7. Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
  8. Platelet count decreased
  9. Proctalgia (pain in the rectum)
  10. Pyrexia (fever)

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Diarrhoea
  2. Colitis microscopic (inflammation of colon with diarrhoea and abdominal cramps)
  3. Febrile neutropenia (fever with reduced white blood cells)
  4. Anxiety
  5. Cholecystitis chronic (long lasting infection of gallbladder)
  6. Depression
  7. Gallbladder disorder
  8. Injury
  9. Pulmonary embolism (blockage of the main artery of the lung)
  10. Weight increased

50-59:

n/a

60+:

  1. Hypotension (abnormally low blood pressure)
  2. Sepsis (a severe blood infection that can lead to organ failure and death)
  3. Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
  4. Rales (an abnormal respiratory sound characterized by fine crackles)
  5. Renal failure (kidney dysfunction)
  6. Convulsions (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled of muscles contract and relax rapidly and repeatedly)
  7. Neutropenia (an abnormally low number of neutrophils)
  8. Platelet count decreased
  9. Thrombocytopenia (decrease of platelets in blood)
  10. Anaemia (lack of blood)

What are the existing conditions these people have? *

  1. Anaesthesia: 7 people, 17.07%
  2. Depression: 5 people, 12.20%
  3. Constipation: 5 people, 12.20%
  4. Nausea (feeling of having an urge to vomit): 4 people, 9.76%
  5. Sedation: 3 people, 7.32%
  6. Multiple Myeloma (cancer of the plasma cells): 3 people, 7.32%
  7. Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 3 people, 7.32%

* Approximation only. Some reports may have incomplete information.

Do you take Cefazolin sodium and Tylenol?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Cefazolin sodium and Tylenol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Cefazolin sodium:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Tylenol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Cefazolin sodium and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Tylenol and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on cefazolin sodium and acetaminophen (the active ingredients of Cefazolin sodium and Tylenol, respectively), and Cefazolin sodium and Tylenol (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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