Cefazolin and Imodium drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Cefazolin (cefazolin sodium) and Imodium (loperamide hydrochloride). Common drug interactions include nausea among females and oedema peripheral among males.

The phase IV clinical study analyzes what interactions people have when they take Cefazolin and Imodium. It is created by eHealthMe based on reports of 72 people who take the same drugs from the FDA, and is updated regularly.

What is Cefazolin?

Cefazolin has active ingredients of cefazolin sodium. It is often used in infection. eHealthMe is studying from 15,157 Cefazolin users. Check the latest studies of Cefazolin.

What is Imodium?

Imodium has active ingredients of loperamide hydrochloride. It is often used in diarrhea. eHealthMe is studying from 45,092 Imodium users. Check the latest studies of Imodium.

On Jul, 15, 2026

72 people who take Cefazolin and Imodium together, and have interactions are studied.

Cefazolin and Imodium drug interactions.

What are the common drug interactions of Cefazolin and Imodium, by gender? *:

female:

Nausea (feeling of having an urge to vomit)
Hypertension (high blood pressure)
Dry skin
Abdominal pain
Arthralgia (joint pain)
Depression
Dizziness
Dyspnoea (difficult or laboured respiration)
Fatigue (feeling of tiredness)
Muscle spasms (muscle contraction)

male:

Oedema peripheral (superficial swelling)
Anaemia (lack of blood)
Nausea (feeling of having an urge to vomit)
Arthralgia (joint pain)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Atrioventricular block (heart block)
Pain
Pneumonia
Anxiety
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)

What are the common drug interactions of Cefazolin and Imodium, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Colitis microscopic (inflammation of colon with diarrhoea and abdominal cramps)
Febrile neutropenia (fever with reduced white blood cells)
Face oedema (swelling of face)
Hyperthermia (body temperature greatly above normal)
Hypoalbuminaemia (levels of albumin in blood serum are abnormally low)
Oedema peripheral (superficial swelling)
Pulmonary embolism (blockage of the main artery of the lung)
Vitamin a deficiency
Vitamin d deficiency
Pyrexia (fever)

50-59:

Hyperuricaemia (level of uric acid in the blood that is abnormally high)
Muscular weakness (muscle weakness)
Cellulitis (infection under the skin)
Chills (felling of cold)
Chronic kidney disease
Device related infection
Ecchymosis (a discoloration of the skin resulting from bleeding underneath)
Erythema (redness of the skin)
Memory impairment
Metabolic encephalopathy (disorder or disease of the brain due to the body's disability to use energy)

60+:

Haemorrhage intracranial (bleeding within the skull)
Leukopenia (less number of white blood cells in blood)
Fatigue (feeling of tiredness)
Febrile neutropenia (fever with reduced white blood cells)
Renal failure (kidney dysfunction)
Abdominal pain
Anaemia (lack of blood)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Atrioventricular block (heart block)
Muscle spasms (muscle contraction)

What are the existing conditions these people have? *

High Blood Pressure: 32 people, 44.44%
Nausea (feeling of having an urge to vomit): 29 people, 40.28%
Depression: 23 people, 31.94%
Stress And Anxiety: 22 people, 30.56%
Insomnia (sleeplessness): 19 people, 26.39%
Pain: 19 people, 26.39%
Hypokalemia (low potassium): 18 people, 25.00%
Anaemia (lack of blood): 15 people, 20.83%
Short-Bowel Syndrome (a condition in which the body cannot absorb enough fluids and nutrients because part of the small intestine is missing): 14 people, 19.44%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 13 people, 18.06%

* Approximation only. Some reports may have incomplete information.

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