Cefixime and Sodium bicarbonate drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Cefixime (cefixime) and Sodium bicarbonate (sodium bicarbonate). Common drug interactions include urinary tract infection bacterial among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Cefixime and Sodium bicarbonate. It is created by eHealthMe based on reports of 55 people who take the same drugs from the FDA, and is updated regularly.

What is Cefixime?

Cefixime has active ingredients of cefixime. eHealthMe is studying from 3,237 Cefixime users. Check the latest studies of Cefixime.

What is Sodium bicarbonate?

Sodium bicarbonate has active ingredients of sodium bicarbonate. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 27,283 Sodium bicarbonate users. Check the latest studies of Sodium bicarbonate.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 30, 2026

55 people who take Cefixime and Sodium bicarbonate together, and have interactions are studied.

Cefixime and Sodium bicarbonate drug interactions.

What are the common drug interactions of Cefixime and Sodium Bicarbonate, by gender? *:

female:

Urinary tract infection bacterial
Back pain
Duodenitis (inflammation of the duodenum)
Abdominal pain
Abdominal pain upper
Activated partial thromboplastin time prolonged
Adrenal insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids)
Alanine aminotransferase increased
Aspartate aminotransferase increased
Blood creatinine increased

male:

Chronic kidney disease
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anaemia (lack of blood)
Anal abscess
Anal erosion
Anal polyp (abnormal growth sticking out from the mucous membrane lining the anus or colon)
Ankle fracture
Asthenia (weakness)
Back pain
Bacteraemia (presence of bacteria in the blood)

What are the common drug interactions of Cefixime and Sodium Bicarbonate, by age (0-1 to 60+)? *:

0-1:

Pyelonephritis acute (sudden inflammation of kidney caused by bacteria)
Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)
Metabolic alkalosis (too much bicarbonate in the blood)

2-9:

n/a

10-19:

Leukopenia (less number of white blood cells in blood)
Lymphopenia (an abnormally low level of lymphocytes in the blood)
Neutropenia (an abnormally low number of neutrophils)
Thrombocytopenia (decrease of platelets in blood)
Gastritis (inflammation of stomach)
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Hypoglycaemia (deficiency of glucose in the bloodstream)
Tonsillitis (inflammation of tonsil)
Upper respiratory tract infection
Gastroenteritis (inflammation of stomach and intestine)

20-29:

n/a

30-39:

Chronic kidney disease
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Ankle fracture
Anxiety
Asthenia (weakness)
Back pain
Dysstasia (difficulty in standing)
Emotional distress
Exercise tolerance decreased
Fatigue (feeling of tiredness)

40-49:

Abdominal distension
Anaemia (lack of blood)
Haematuria (presence of blood in urine)
Hyperkalaemia (damage to or disease of the kidney)
Urinary tract infection

50-59:

General physical condition
Abdominal pain upper
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Chronic kidney disease
Emotional distress
Gastroenteritis viral (inflammation of stomach and intestine caused by virus infection)
Memory impairment
Osteopenia (a condition where bone mineral density is lower than normal)
Pain

60+:

Urinary tract infection
Haematuria (presence of blood in urine)
Paraesthesia oral (sensation of tingling, tickling, prickling, pricking, or burning of a person's oral with no apparent long-term physical effect)
Procedural pain
Weight decreased
Anaemia (lack of blood)
Hypotension (abnormally low blood pressure)
Pneumonia klebsiella (pneumonia caused by bacteria klebsiella)
Urinary tract infection bacterial
Back pain

What are the existing conditions these people have? *

Urinary Tract Infection: 16 people, 29.09%
Metabolic Acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body): 13 people, 23.64%
Short-Bowel Syndrome (a condition in which the body cannot absorb enough fluids and nutrients because part of the small intestine is missing): 13 people, 23.64%
Osteoporosis (bones weak and more likely to break): 11 people, 20.00%
Oropharyngeal Candidiasis (fungal infection of oropharynx): 11 people, 20.00%
Hypokalemia (low potassium): 11 people, 20.00%
Sepsis (a severe blood infection that can lead to organ failure and death): 11 people, 20.00%
Hyperkalemia (damage to or disease of the kidney): 9 people, 16.36%
Depression: 6 people, 10.91%
Refractory Cancer (cancer that has not responded to treatment): 5 people, 9.09%

* Approximation only. Some reports may have incomplete information.

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