Ceftin and Linzess drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Ceftin (cefuroxime axetil) and Linzess (linaclotide). Common drug interactions include nausea among females and chemotherapy among males.

The phase IV clinical study analyzes what interactions people have when they take Ceftin and Linzess. It is created by eHealthMe based on reports of 21 people who take the same drugs from the FDA, and is updated regularly.

What is Ceftin?

Ceftin has active ingredients of cefuroxime axetil. It is often used in sinusitis. eHealthMe is studying from 4,333 Ceftin users. Check the latest studies of Ceftin.

What is Linzess?

Linzess has active ingredients of linaclotide. It is often used in constipation. eHealthMe is studying from 24,086 Linzess users. Check the latest studies of Linzess.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 15, 2026

21 people who take Ceftin and Linzess together, and have interactions are studied.

What are the common drug interactions of Ceftin and Linzess, by gender? *:

female:

Nausea (feeling of having an urge to vomit)
Hyperhidrosis (abnormally increased sweating)
Mobility decreased (ability to move is reduced)
Abdominal discomfort
Abnormal behaviour
Alanine aminotransferase increased
Anaemia (lack of blood)
Arrhythmia (irregular heartbeat)
Aspartate aminotransferase increased
Asthma

male:

Chemotherapy

What are the common drug interactions of Ceftin and Linzess, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Abdominal discomfort
Abnormal behaviour
Alanine aminotransferase increased
Anaemia (lack of blood)
Arrhythmia (irregular heartbeat)
Arthralgia (joint pain)
Aspartate aminotransferase increased
Asthma
Bacterial infection
Blood bilirubin increased

40-49:

Chronic kidney disease
Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
Depression
Fatigue (feeling of tiredness)
Gastrointestinal disorder (functional problems of gastrointestinal tract)
Mobility decreased (ability to move is reduced)
Muscle spasticity (tight or stiff muscles and an inability to control those muscles)
Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
Pain
Renal failure (kidney dysfunction)

50-59:

n/a

60+:

Hypertension (high blood pressure)
Chemotherapy
Pain
Pneumonia
Contusion (a type of hematoma of tissue in which capillaries)
Death
Decreased appetite
Dysuria (painful or difficult urination)
Emotional disorder
Headache (pain in head)

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 9 people, 42.86%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 6 people, 28.57%
Urinary Tract Infection: 3 people, 14.29%
Stress And Anxiety: 3 people, 14.29%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 9.52%
Pain: 2 people, 9.52%
Nausea (feeling of having an urge to vomit): 2 people, 9.52%
Infection: 2 people, 9.52%
Hypersensitivity: 2 people, 9.52%
High Blood Cholesterol: 2 people, 9.52%

* Approximation only. Some reports may have incomplete information.

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