Ceftriaxone sodium and Cefixime drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Ceftriaxone sodium (ceftriaxone sodium) and Cefixime (cefixime). Common drug interactions include emotional distress among females and acute respiratory distress syndrome among males.

The phase IV clinical study analyzes what interactions people have when they take Ceftriaxone sodium and Cefixime. It is created by eHealthMe based on reports of 36 people who take the same drugs from the FDA, and is updated regularly.

What is Ceftriaxone sodium?

Ceftriaxone sodium has active ingredients of ceftriaxone sodium. eHealthMe is studying from 6,549 Ceftriaxone sodium users. Check the latest studies of Ceftriaxone sodium.

What is Cefixime?

Cefixime has active ingredients of cefixime. eHealthMe is studying from 3,237 Cefixime users. Check the latest studies of Cefixime.



On Jul, 10, 2026

36 people who take Ceftriaxone sodium and Cefixime together, and have interactions are studied.

Ceftriaxone sodium and Cefixime drug interactions.

What are the common drug interactions of Ceftriaxone Sodium and Cefixime, by gender? *:

female:

  1. Emotional distress
  2. Fatigue (feeling of tiredness)
  3. Fistula (an abnormal connection or passageway between two)
  4. Macular degeneration (painless eye condition that leads to the gradual loss of central vision)
  5. Mobility decreased (ability to move is reduced)
  6. Muscle contracture (a permanent shortening of a muscle)
  7. Ocular hypertension (intraocular pressure higher than normal)
  8. Oropharyngeal pain
  9. Osteopenia (a condition where bone mineral density is lower than normal)
  10. Osteoporosis (bones weak and more likely to break)

male:

  1. Acute respiratory distress syndrome
  2. Pneumothorax (the presence of air or gas in the cavity between the lungs and the chest wall, causing collapse of the lung)
  3. Pneumonia mycoplasmal (mycoplasma pneumonia (mp) is a contagious respiratory infection)
  4. Post-traumatic pain
  5. Pruritus (severe itching of the skin)
  6. Rash
  7. Rhinitis (a medical term for irritation and inflammation of the mucous membrane inside the nose)
  8. Rhinorrhoea (watery mucus discharge from the nose)
  9. Sneezing
  10. Upper respiratory tract infection

What are the common drug interactions of Ceftriaxone Sodium and Cefixime, by age (0-1 to 60+)? *:

0-1:

  1. Acute respiratory distress syndrome
  2. Pneumothorax (the presence of air or gas in the cavity between the lungs and the chest wall, causing collapse of the lung)
  3. Cytomegalovirus infection
  4. Immunodeficiency
  5. Infection
  6. Pleural effusion (water on the lungs)
  7. Pneumonia bacterial (pneumonia associated with bacterial infection)
  8. Pneumonia cytomegaloviral (cmv pneumonia is caused by a member of a group of herpes-type viruses)
  9. Drug ineffective

2-9:

n/a

10-19:

  1. Asthma
  2. Cough
  3. Heat exhaustion (dizziness and nausea and weakness caused by depletion of body fluids and electrolytes)
  4. Overweight
  5. Pneumonia mycoplasmal (mycoplasma pneumonia (mp) is a contagious respiratory infection)
  6. Pruritus (severe itching of the skin)
  7. Rash
  8. Rhinitis (a medical term for irritation and inflammation of the mucous membrane inside the nose)
  9. Rhinorrhoea (watery mucus discharge from the nose)
  10. Sneezing

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Angioedema (rapid swelling of the dermis)
  2. Abdominal pain upper
  3. Anaphylactic shock (severe and rapid and sometimes fatal hypersensitivity reaction to a substance)
  4. Chest pain
  5. Cough
  6. Cyanosis (lack of oxygen in body leads to blue appearance of skin ,mucous membrane nails)
  7. Pallor
  8. Peripheral coldness
  9. Pulse absent
  10. Respiratory distress (difficulty in breathing)

60+:

  1. Urinary tract infection
  2. Haematuria (presence of blood in urine)
  3. Urinary tract infection bacterial
  4. Urinary tract infection staphylococcal
  5. General physical health deterioration (weak health status)
  6. Large intestinal obstruction
  7. Anaemia of chronic disease
  8. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  9. Anxiety
  10. Carpal tunnel syndrome (nerve compression at wrist results numbness weakness, pain , swelling)

What are the existing conditions these people have? *

  1. Urinary Tract Infection: 7 people, 19.44%
  2. Osteoporosis (bones weak and more likely to break): 7 people, 19.44%
  3. Hyperkalemia (damage to or disease of the kidney): 7 people, 19.44%
  4. Hypokalemia (low potassium): 7 people, 19.44%
  5. Short-Bowel Syndrome (a condition in which the body cannot absorb enough fluids and nutrients because part of the small intestine is missing): 7 people, 19.44%
  6. Oropharyngeal Candidiasis (fungal infection of oropharynx): 7 people, 19.44%
  7. Metabolic Acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body): 7 people, 19.44%
  8. Sepsis (a severe blood infection that can lead to organ failure and death): 7 people, 19.44%
  9. Allergies: 5 people, 13.89%
  10. Haematuria (presence of blood in urine): 4 people, 11.11%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Ceftriaxone sodium and Cefixime:

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Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Ceftriaxone sodium:

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Browse all side effects of Cefixime:

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Browse all interactions between Ceftriaxone sodium and drugs from A to Z:

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Browse all interactions between Cefixime and drugs from A to Z:

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Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on ceftriaxone sodium and cefixime (the active ingredients of Ceftriaxone sodium and Cefixime, respectively), and Ceftriaxone sodium and Cefixime (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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