Ceftriaxone and Bumex drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Ceftriaxone (ceftriaxone sodium) and Bumex (bumetanide). Common drug interactions include alanine aminotransferase increased among females and pneumonia among males.

The phase IV clinical study analyzes what interactions people have when they take Ceftriaxone and Bumex. It is created by eHealthMe based on reports of 59 people who take the same drugs from the FDA, and is updated regularly.

What is Ceftriaxone?

Ceftriaxone has active ingredients of ceftriaxone sodium. It is often used in typhoid fever. eHealthMe is studying from 40,991 Ceftriaxone users. Check the latest studies of Ceftriaxone.

What is Bumex?

Bumex has active ingredients of bumetanide. It is often used in swelling. eHealthMe is studying from 9,210 Bumex users. Check the latest studies of Bumex.

On Aug, 12, 2026

59 people who take Ceftriaxone and Bumex together, and have interactions are studied.

Ceftriaxone and Bumex drug interactions.

What are the common drug interactions of Ceftriaxone and Bumex, by gender? *:

female:

Alanine aminotransferase increased
Aspartate aminotransferase increased
Blood alkaline phosphatase increased
Blood bilirubin increased
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Dyspnoea exertional (breathlessness or shortness of breath)
Hepatosplenomegaly (enlargement of both the liver and the spleen)
Hepatotoxicity (chemical-driven liver damage)
Hyperbilirubinaemia (excess of bilirubin in the blood)
Infection

male:

Pneumonia
Cardiac failure congestive
Arrhythmia (irregular heartbeat)
Azotaemia (excess of urea or other nitrogenous compounds in the blood)
Cardiac output decreased
Cerebellar ischaemia (lack of blood supply to cerebeller)
Haematoma (collection of blood outside the blood vessels)
Haemolysis (breaking open of red blood cells and the release of haemoglobin into the surrounding fluid)
Septic shock (shock due to blood infection)
Thrombocytopenia (decrease of platelets in blood)

What are the common drug interactions of Ceftriaxone and Bumex, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Extravasation (leakage of a fluid)

10-19:

n/a

20-29:

Pain
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Depression
Anaemia (lack of blood)
Cardiac failure
Chest discomfort
Chest pain
Chills (felling of cold)
Cough
Decreased appetite

30-39:

Fluid overload (too much fluid in the blood)
Platelet count decreased
Renal failure (kidney dysfunction)
Acute respiratory distress syndrome
Alanine aminotransferase increased
Aspartate aminotransferase increased
Blood albumin decreased
Blood alkaline phosphatase nos increased
Blood creatinine increased
Blood urea increased

40-49:

Chronic kidney disease
Pain
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Respiratory failure (inadequate gas exchange by the respiratory system)
Sepsis (a severe blood infection that can lead to organ failure and death)
Abdominal pain
Abdominal pain upper
Alanine aminotransferase increased
Aspartate aminotransferase increased
Blood alkaline phosphatase increased

50-59:

Aortic thrombosis (formation of a blood clot inside aorta)
Ascites (accumulation of fluid in the abdominal cavity)
Hypovolaemia (a decreased volume of circulating blood in the body)
Bacteraemia (presence of bacteria in the blood)
Ischaemic cardiomyopathy (weakness in the muscle of the heart due to inadequate oxygen delivery to the myocardium with coronary artery disease)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Chronic kidney disease
Confusional state
Neutropenia (an abnormally low number of neutrophils)
Arrhythmia (irregular heartbeat)

60+:

Pneumonia
Atrial flutter (an abnormal heart rhythm that occurs in the atria of the heart)
Death
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Delirium (wild excitement)
Dyspnoea (difficult or laboured respiration)
Thrombocytopenia (decrease of platelets in blood)
Ventricular tachycardia (rapid heartbeat that originates in one of the lower chambers (the ventricles) of the heart)
Abdominal wound dehiscence (abdominal wound ruptures)
Adrenal insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids)

What are the existing conditions these people have? *

Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 13 people, 22.03%
Nausea (feeling of having an urge to vomit): 11 people, 18.64%
Pneumonia: 8 people, 13.56%
Stress And Anxiety: 7 people, 11.86%
Cardiac Disorder: 7 people, 11.86%
Pain: 7 people, 11.86%
Diabetes: 6 people, 10.17%
Infection: 6 people, 10.17%
High Blood Pressure: 5 people, 8.47%
High Blood Cholesterol: 5 people, 8.47%

* Approximation only. Some reports may have incomplete information.

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