Ceftriaxone and Risperdal drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Ceftriaxone (ceftriaxone sodium) and Risperdal (risperidone). Common drug interactions include hyperthermia among females and cardio-respiratory arrest among males.

The phase IV clinical study analyzes what interactions people have when they take Ceftriaxone and Risperdal. It is created by eHealthMe based on reports of 83 people who take the same drugs from the FDA, and is updated regularly.

What is Ceftriaxone?

Ceftriaxone has active ingredients of ceftriaxone sodium. It is often used in typhoid fever. eHealthMe is studying from 40,991 Ceftriaxone users. Check the latest studies of Ceftriaxone.

What is Risperdal?

Risperdal has active ingredients of risperidone. It is often used in bipolar disorder. eHealthMe is studying from 127,729 Risperdal users. Check the latest studies of Risperdal.

On Jul, 16, 2026

83 people who take Ceftriaxone and Risperdal together, and have interactions are studied.

Ceftriaxone and Risperdal drug interactions.

What are the common drug interactions of Ceftriaxone and Risperdal, by gender? *:

female:

Hyperthermia (body temperature greatly above normal)
Inflammation
Peritonitis (inflammation of the peritoneum, the thin tissue that lines the inner wall of the abdomen and covers most of the abdominal organs)
Orthostatic hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up)
Grand mal convulsion (a type of generalized seizure that affects the entire brain)
Orthostatic hypertension (a medical condition consisting of a sudden increase in blood pressure when a person stands up)
White blood cell count decreased
C-reactive protein increased
Neutrophil count increased (excess than normal number of neutrophil a type of blood cell)
Depression

male:

Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
Death
Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
Erythema multiforme (a type of hypersensitivity reaction)
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Hypertension (high blood pressure)
Hypotension (abnormally low blood pressure)
Lip erosion (peeling off of lip)
Lip swelling

What are the common drug interactions of Ceftriaxone and Risperdal, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Convulsions (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled of muscles contract and relax rapidly and repeatedly)

10-19:

Blood creatine phosphokinase increased
Extrapyramidal disorder (involuntary muscle spasms in the face and neck)
Neuroleptic malignant syndrome (a life-threatening neurological disorder most often caused by an adverse reaction to neuroleptic or antipsychotic agents)
Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
Neck pain
Hepatocellular injury (liver injury)

20-29:

Appendicitis (inflammation of the appendix)
Dizziness
Fall
Gastrointestinal perforation (hole in the digestive tract)
Grand mal convulsion (a type of generalized seizure that affects the entire brain)
Infectious peritonitis (inflammation of the peritoneum, typically caused by bacterial infection)
Leukopenia (less number of white blood cells in blood)
Neutropenia (an abnormally low number of neutrophils)
Orthostatic hypertension (a medical condition consisting of a sudden increase in blood pressure when a person stands up)
White blood cell count decreased

30-39:

Blood pressure increased
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Constipation
Depression
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Diarrhoea
Gastric ulcer (stomach ulcer)
Gastroenteritis (inflammation of stomach and intestine)
Hypersensitivity
Immunosuppression

40-49:

Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
Death
Myoclonus (a brief, involuntary twitching of a muscle or a group of muscles)
Nervous system disorder (a general class of medical conditions affecting the nervous system)
Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
Urinary tract infection
Cervix disorder
Chronic kidney disease
Constipation
Cough

50-59:

Orthostatic hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up)
Anaemia (lack of blood)
C-reactive protein increased
Depression
Grand mal convulsion (a type of generalized seizure that affects the entire brain)
Hip arthroplasty
Infection
Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
Neutrophil count increased (excess than normal number of neutrophil a type of blood cell)
Orthostatic hypertension (a medical condition consisting of a sudden increase in blood pressure when a person stands up)

60+:

Pyrexia (fever)
Platelet count decreased
Blood cholesterol increased
Dementia (madness)
Drug ineffective
Erythema multiforme (a type of hypersensitivity reaction)
Hepatic encephalopathy (spectrum of neuropsychiatric abnormalities in patients with liver failure)
Hypertension (high blood pressure)
Sudden death
Tachycardia (a heart rate that exceeds the range of 100 beats/min)

What are the existing conditions these people have? *

Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 10 people, 12.05%
Delirium (wild excitement): 10 people, 12.05%
High Blood Pressure: 9 people, 10.84%
Pain: 8 people, 9.64%
Agitation (state of anxiety or nervous excitement): 7 people, 8.43%
Urinary Tract Infection: 6 people, 7.23%
Sedation: 6 people, 7.23%
Fever: 5 people, 6.02%

* Approximation only. Some reports may have incomplete information.

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