Celebrex and Moduretic 5-50 drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Celebrex (celecoxib) and Moduretic 5-50 (amiloride hydrochloride; hydrochlorothiazide). Common drug interactions include herpes zoster among females and anaemia among males.

The phase IV clinical study analyzes what interactions people have when they take Celebrex and Moduretic 5-50. It is created by eHealthMe based on reports of 52 people who take the same drugs from the FDA, and is updated regularly.

What is Celebrex?

Celebrex has active ingredients of celecoxib. It is often used in arthritis. eHealthMe is studying from 151,105 Celebrex users. Check the latest studies of Celebrex.

What is Moduretic 5-50?

Moduretic 5-50 has active ingredients of amiloride hydrochloride; hydrochlorothiazide. It is often used in high blood pressure. eHealthMe is studying from 3,224 Moduretic 5-50 users. Check the latest studies of Moduretic 5-50.



On Jul, 26, 2026

52 people who take Celebrex and Moduretic 5-50 together, and have interactions are studied.

Celebrex and Moduretic 5-50 drug interactions.

What are the common drug interactions of Celebrex and Moduretic 5-50, by gender? *:

female:

  1. Herpes zoster
  2. Peptic ulcer
  3. Anxiety
  4. Anxiety disorder
  5. Aortic arteriosclerosis (hardening of the aortic arteries)
  6. Aortic stenosis (obstruction to the outflow of blood from the left ventricle into the aorta)
  7. Aortic valve incompetence
  8. Arthropathy
  9. Back pain
  10. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)

male:

  1. Anaemia (lack of blood)
  2. Haemorrhage (bleeding)
  3. Haematemesis (vomiting of blood)
  4. Haematochezia (passage of stools containing blood)
  5. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
  6. Injury
  7. Lymphadenopathy (disease or enlargement of lymph nodes)
  8. Ocular icterus (presence of jaundice seen in the sclera of the eye)
  9. Osteonecrosis of jaw (death of bone of jaw)
  10. Pathological fracture (broken bone caused by disease)

What are the common drug interactions of Celebrex and Moduretic 5-50, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Anaphylactic reaction (serious allergic reaction)
  2. Arterial embolism limb
  3. Headache (pain in head)
  4. Rash pruritic (redness with itching)

50-59:

  1. Depression
  2. Herpes zoster
  3. Mood altered (changes in mood)
  4. Status epilepticus (a life-threatening condition in which the brain is in a state of persistent seizure)
  5. Suicidal ideation
  6. Cellulitis (infection under the skin)

60+:

  1. Anxiety
  2. Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
  3. Haemorrhage (bleeding)
  4. Anxiety disorder
  5. Aortic arteriosclerosis (hardening of the aortic arteries)
  6. Aortic stenosis (obstruction to the outflow of blood from the left ventricle into the aorta)
  7. Aortic valve incompetence
  8. Arthropathy
  9. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  10. Carpal tunnel syndrome (nerve compression at wrist results numbness weakness, pain , swelling)

What are the existing conditions these people have? *

  1. Diabetes: 4 people, 7.69%
  2. Depression: 4 people, 7.69%
  3. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 3 people, 5.77%
  4. Pain: 3 people, 5.77%
  5. Osteoarthritis (a joint disease caused by cartilage loss in a joint): 3 people, 5.77%

* Approximation only. Some reports may have incomplete information.

Do you take Celebrex and Moduretic 5-50?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Celebrex and Moduretic 5-50:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Celebrex:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Moduretic 5-50:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Celebrex and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Moduretic 5-50 and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on celecoxib and amiloride hydrochloride; hydrochlorothiazide (the active ingredients of Celebrex and Moduretic 5-50, respectively), and Celebrex and Moduretic 5-50 (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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