Fluorouracil and Lymphocytosis - a phase IV clinical study of FDA data

Summary:

Lymphocytosis is reported as a side effect among people who take Fluorouracil (fluorouracil), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Cyclophosphamide, and have Breast cancer.

The phase IV clinical study analyzes which people have Lymphocytosis when taking Fluorouracil. It is created by eHealthMe based on reports of 96,940 people who have side effects when taking Fluorouracil from the FDA, and is updated regularly.

What is Fluorouracil?

Fluorouracil has active ingredients of fluorouracil. It is often used in colon cancer metastatic. eHealthMe is studying from 97,087 Fluorouracil users. Check the latest studies of Fluorouracil.

What is Lymphocytosis?

Lymphocytosis (an increase in the number or proportion of lymphocytes in the blood) is found to be associated with 305 drugs and 495 conditions by eHealthMe. Check the latest studies of Lymphocytosis.



On Jul, 26, 2026

96,940 people reported to have side effects when taking Fluorouracil.
Among them, 13 people (0.01%) have Lymphocytosis.

Could Fluorouracil cause Lymphocytosis?

Among these 13 people:

How long have people been on Fluorouracil when they have Lymphocytosis? *

  • < 1 month: 50 %
  • 1 - 6 months: 50 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Lymphocytosis when taking Fluorouracil? *

  • female: 100 %
  • male: 0.0 %

What is the age of people who have Lymphocytosis when taking Fluorouracil? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 33.33 %
  • 50-59: 0.0 %
  • 60+: 66.67 %

What are other drugs people take besides Fluorouracil? *

  1. Cyclophosphamide: 3 people, 23.08%
  2. Prednisolone: 2 people, 15.38%
  3. Methotrexate: 2 people, 15.38%
  4. Zocor: 1 person, 7.69%
  5. Dexamethasone: 1 person, 7.69%
  6. Amlodipine Besylate: 1 person, 7.69%
  7. Augmentin '125': 1 person, 7.69%
  8. Cimetidine: 1 person, 7.69%
  9. Cytarabine: 1 person, 7.69%
  10. Cytoxan: 1 person, 7.69%

What are other side effects people have besides Lymphocytosis? *

  1. Weakness: 7 people, 53.85%
  2. Fever: 7 people, 53.85%
  3. C-Reactive Protein Increased: 6 people, 46.15%
  4. Mucosal Inflammation (infection of mucous membrane): 4 people, 30.77%
  5. Hyperkalemia (damage to or disease of the kidney): 4 people, 30.77%
  6. Septic Shock (shock due to blood infection): 4 people, 30.77%
  7. Pneumonia: 4 people, 30.77%
  8. Blood Lactate Dehydrogenase Increased: 4 people, 30.77%
  9. Cough: 4 people, 30.77%
  10. Multi-Organ Failure (multisystem organ failure): 4 people, 30.77%

What are the existing conditions these people have? *

  1. Breast Cancer: 5 people, 38.46%
  2. Neoplasm Malignant (cancer tumour): 3 people, 23.08%
  3. Breast Cancer Stage Ii: 3 people, 23.08%
  4. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 7.69%
  5. Pancreatic Carcinoma (pancreatic cancer): 1 person, 7.69%
  6. Leukocytosis (increased white blood cells): 1 person, 7.69%
  7. Breast Cancer Metastatic: 1 person, 7.69%
  8. Anaemia (lack of blood): 1 person, 7.69%
  9. Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Fluorouracil and have Lymphocytosis?

- Check whether Lymphocytosis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Fluorouracil:

Lymphocytosis treatments and more:

How severe was Lymphocytosis and when was it recovered:

Expand to all the drugs that have ingredients of fluorouracil:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Fluorouracil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Lymphocytosis:

Browse all the conditions that are associated with Lymphocytosis:


How the study uses the data?

The study uses data from the FDA. It is based on fluorouracil (the active ingredients of Fluorouracil) and Fluorouracil (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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