Celexa and Duragesic-50 drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Celexa (citalopram hydrobromide) and Duragesic-50 (fentanyl). Common drug interactions include drug effect decreased among females and anaemia among males.

The phase IV clinical study analyzes what interactions people have when they take Celexa and Duragesic-50. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.

What is Celexa?

Celexa has active ingredients of citalopram hydrobromide. It is often used in depression. eHealthMe is studying from 56,390 Celexa users. Check the latest studies of Celexa.

What is Duragesic-50?

Duragesic-50 has active ingredients of fentanyl. It is often used in pain. eHealthMe is studying from 733 Duragesic-50 users. Check the latest studies of Duragesic-50.



On Jul, 16, 2026

11 people who take Celexa and Duragesic-50 together, and have interactions are studied.

Celexa and Duragesic-50 drug interactions.

What are the common drug interactions of Celexa and Duragesic-50, by gender? *:

female:

  1. Drug effect decreased
  2. Dyspnoea (difficult or laboured respiration)
  3. Erythema multiforme (a type of hypersensitivity reaction)
  4. Haematuria (presence of blood in urine)
  5. Hyperglycaemia (high blood sugar)
  6. Hypokalaemia (low potassium)
  7. Hypoxia (low oxygen in tissues)
  8. Injection site urticaria (rash of round, red welts on the skin at injection site)
  9. International normalised ratio increased
  10. Lung infiltration (a substance that normally includes fluid, inflammatory exudates or cells that fill a region of lung)

male:

  1. Anaemia (lack of blood)
  2. Asthenia (weakness)
  3. Calculus ureteric (stone in ureter)
  4. Cardiomegaly (increased size of heart than normal)
  5. Chest pain
  6. Compression fracture (fracture due to pressure caused by injury)
  7. Confusional state
  8. Decreased appetite
  9. Decubitus ulcer (a chronic ulcer of the skin caused by prolonged pressure on it)
  10. Diarrhoea

What are the common drug interactions of Celexa and Duragesic-50, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Osteonecrosis (death of bone)
  2. Pancreatic disorder
  3. Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
  4. Post procedural haemorrhage (post procedural bleeding)
  5. Pulmonary oedema (fluid accumulation in the lungs)
  6. Rash pruritic (redness with itching)
  7. Renal failure acute (rapid kidney dysfunction)
  8. Respiratory failure (inadequate gas exchange by the respiratory system)
  9. Respiratory syncytial virus infection (viral disease of respiratory system)
  10. Sepsis (a severe blood infection that can lead to organ failure and death)

40-49:

  1. Abdominal pain
  2. Anaemia (lack of blood)
  3. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  4. Arthropathy
  5. Asthenia (weakness)
  6. Atelectasis (partial or complete collapse of the lung)
  7. Back pain
  8. Bone disorder
  9. Calculus ureteric (stone in ureter)
  10. Cardiomegaly (increased size of heart than normal)

50-59:

  1. Disturbance in attention
  2. Formication (a sensation that exactly resembles that of small insects crawling on (or under) the skin)
  3. Leukocytosis (increased white blood cells)
  4. Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
  5. Palpitations (feelings or sensations that your heart is pounding or racing)
  6. Pyrexia (fever)
  7. Syncope (loss of consciousness with an inability to maintain postural tone)
  8. Ulcer
  9. Vomiting
  10. Agitation (state of anxiety or nervous excitement)

60+:

  1. Anaemia (lack of blood)
  2. Chest pain
  3. Constipation
  4. Dyspnoea (difficult or laboured respiration)
  5. Erythema multiforme (a type of hypersensitivity reaction)
  6. Hypoxia (low oxygen in tissues)
  7. Pyrexia (fever)

What are the existing conditions these people have? *

  1. Sleep Disorder: 2 people, 18.18%
  2. Stress And Anxiety: 1 person, 9.09%
  3. Quit Smoking: 1 person, 9.09%
  4. Neuropathy Peripheral (surface nerve damage): 1 person, 9.09%
  5. Nausea (feeling of having an urge to vomit): 1 person, 9.09%
  6. Lung Cancer - Non-Small Cell (lung cancer): 1 person, 9.09%
  7. Hypersensitivity: 1 person, 9.09%
  8. High Blood Pressure: 1 person, 9.09%
  9. Dyslipidaemia (abnormal amount of lipids): 1 person, 9.09%
  10. Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Celexa and Duragesic-50:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Celexa:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Duragesic-50:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Celexa and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Duragesic-50 and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on citalopram hydrobromide and fentanyl (the active ingredients of Celexa and Duragesic-50, respectively), and Celexa and Duragesic-50 (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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