Celexa and Kadian drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Celexa (citalopram hydrobromide) and Kadian (morphine sulfate). Common drug interactions include wheezing among females and nasopharyngitis among males.

The phase IV clinical study analyzes what interactions people have when they take Celexa and Kadian. It is created by eHealthMe based on reports of 41 people who take the same drugs from the FDA, and is updated regularly.

What is Celexa?

Celexa has active ingredients of citalopram hydrobromide. It is often used in depression. eHealthMe is studying from 56,391 Celexa users. Check the latest studies of Celexa.

What is Kadian?

Kadian has active ingredients of morphine sulfate. It is often used in pain. eHealthMe is studying from 23,045 Kadian users. Check the latest studies of Kadian.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Sep, 03, 2026

41 people who take Celexa and Kadian together, and have interactions are studied.

Celexa and Kadian drug interactions.

What are the common drug interactions of Celexa and Kadian, by gender? *:

female:

  1. Wheezing (a high-pitched whistling sound made while you breath)
  2. Cardiac failure congestive
  3. Emphysema (chronic respiratory disease - over inflation of the air sacs (alveoli) in the lungs)
  4. Hypertensive heart disease
  5. Cardiomegaly (increased size of heart than normal)
  6. Drug ineffective
  7. Hepatic lesion
  8. Hyperlipidaemia (presence of excess lipids in the blood)
  9. Hypoaesthesia (reduced sense of touch or sensation)
  10. Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)

male:

  1. Nasopharyngitis (inflammation of the nasopharynx)
  2. Essential tremor
  3. Chest pain
  4. Colitis (inflammation of colon)
  5. Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
  6. Cough
  7. Creatinine renal clearance decreased
  8. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  9. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  10. Diabetic retinopathy (damage to the retina caused by complications of diabetes)

What are the common drug interactions of Celexa and Kadian, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Jaundice (a yellowish pigmentation of the skin, the conjunctival membranes)
  2. Laryngitis (inflammation of the larynx)
  3. Lung neoplasm (tumour of lung)
  4. Malaise (a feeling of general discomfort or uneasiness)
  5. Metastases to meninges (cancer spreads to meninges)
  6. Mucosal inflammation (infection of mucous membrane)
  7. Odynophagia (painful swallowing, in the mouth (oropharynx) or oesophagus)
  8. Oedema peripheral (superficial swelling)
  9. Osteomyelitis (infection of bone)
  10. Osteonecrosis of jaw (death of bone of jaw)

50-59:

  1. Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
  2. Hip arthroplasty
  3. Appetite increased (increased appetite is when you want to eat much more often or in larger quantities than your body requires)
  4. Colitis (inflammation of colon)
  5. Constipation
  6. Creatinine renal clearance decreased
  7. Headache (pain in head)
  8. Hypertensive heart disease
  9. Stevens-johnson syndrome (an immune-complex-mediated hypersensitivity disorder. it ranges from mild skin and mucous membrane lesions to a severe)
  10. Sweating increased (excess sweating)

60+:

  1. Pneumonia
  2. Cardiac failure congestive
  3. Breast cancer female
  4. Cardiac hypertrophy (thickening of the heart muscle)
  5. Carpal tunnel syndrome (nerve compression at wrist results numbness weakness, pain , swelling)
  6. Constipation
  7. Dizziness
  8. Drug ineffective
  9. Essential tremor
  10. Hydrocephalus (water on the brain)

What are the existing conditions these people have? *

  1. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 8 people, 19.51%
  2. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 7 people, 17.07%
  3. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 7 people, 17.07%
  4. Back Pain: 7 people, 17.07%
  5. High Blood Pressure: 6 people, 14.63%
  6. Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 6 people, 14.63%
  7. Breast Cancer: 6 people, 14.63%

* Approximation only. Some reports may have incomplete information.

Do you take Celexa and Kadian?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Celexa and Kadian:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Celexa:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Kadian:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Celexa and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Kadian and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on citalopram hydrobromide and morphine sulfate (the active ingredients of Celexa and Kadian, respectively), and Celexa and Kadian (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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