Celexa and Nuedexta drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Celexa (citalopram hydrobromide) and Nuedexta (dextromethorphan hydrobromide; quinidine sulfate). Common drug interactions include drug administration error among females and fall among males.
The phase IV clinical study analyzes what interactions people have when they take Celexa and Nuedexta. It is created by eHealthMe based on reports of 55 people who take the same drugs from the FDA, and is updated regularly.
What is Celexa?
Celexa has active ingredients of citalopram hydrobromide. It is often used in depression. eHealthMe is studying from 56,390 Celexa users. Check the latest studies of Celexa.
What is Nuedexta?
Nuedexta has active ingredients of dextromethorphan hydrobromide; quinidine sulfate. eHealthMe is studying from 3,781 Nuedexta users. Check the latest studies of Nuedexta.
55 people who take Celexa and Nuedexta together, and have interactions are studied.

What are the common drug interactions of Celexa and Nuedexta, by gender? *:
female:
- Drug administration error
- Dyschezia (difficulty in defecating)
- Dysgraphia (impaired ability to learn to write)
- Emphysema (chronic respiratory disease - over inflation of the air sacs (alveoli) in the lungs)
- Epistaxis (bleed from the nose)
- Essential hypertension (primary hypertension)
- Fatigue (feeling of tiredness)
- Fine motor delay (delayed movements and actions of the muscles)
- Flushing (the warm, red condition of human skin)
- Gastric disorder (disease of stomach)
male:
- Fall
- Serotonin syndrome (occurs when two drugs that affect the body's level of serotonin are taken together at the same time)
- Resting tremor (an involuntary somewhat rhythmic, muscle contraction and relaxation during resting condition)
- Skull fracture
- Disease progression
- Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
- Weight decreased
- Aggression
- Apathy
- Arthralgia (joint pain)
What are the common drug interactions of Celexa and Nuedexta, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Panic attack
40-49:
- Dizziness
- Nausea (feeling of having an urge to vomit)
- Abnormal behaviour
- Anger
- Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
- Seizure (abnormal excessive or synchronous neuronal activity in the brain)
- Somnolence (a state of near-sleep, a strong desire for sleep)
- Suicidal ideation
- Dysuria (painful or difficult urination)
- Urinary retention (the inability to completely or partially empty the bladder)
50-59:
- Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
- Pneumonia
- Presyncope
- Pulmonary congestion (congestion in the lungs)
- Pyrexia (fever)
- Rhinorrhoea (watery mucus discharge from the nose)
- Road traffic accident
- Varicella
- Vitamin d decreased
- Weight decreased
60+:
- Agitation (state of anxiety or nervous excitement)
- Decreased appetite
- Therapeutic response unexpected
- Disease progression
- Failure to thrive (inadequate weight gain and physical growth in children)
- Weight decreased
- Acute myocardial infarction (acute heart attack)
- Aggression
- Anaemia (lack of blood)
- Arthralgia (joint pain)
What are the existing conditions these people have? *
- Affect Lability (emotional incontinence): 28 people, 50.91%
- Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 12 people, 21.82%
- Insomnia (sleeplessness): 6 people, 10.91%
- Neuropathy Peripheral (surface nerve damage): 5 people, 9.09%
- Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 4 people, 7.27%
- Muscle Spasms (muscle contraction): 4 people, 7.27%
- Essential Tremor: 4 people, 7.27%
- Dementia (madness): 4 people, 7.27%
- Back Pain: 4 people, 7.27%
- Agitation (state of anxiety or nervous excitement): 4 people, 7.27%
* Approximation only. Some reports may have incomplete information.
Do you take Celexa and Nuedexta?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Celexa and Nuedexta:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Celexa:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Nuedexta:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Celexa and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Nuedexta and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Hosseini, S. H., & Ahmadi, A., "Peripheral edema occurring during treatment with risperidone combined with citalopram", Case reports in medicine, 2012 Jan .
- Hosseini, S. H., & Ahmadi, A., "Peripheral edema occurring during treatment with risperidone combined with citalopram", Case reports in medicine, 2012 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on citalopram hydrobromide and dextromethorphan hydrobromide; quinidine sulfate (the active ingredients of Celexa and Nuedexta, respectively), and Celexa and Nuedexta (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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