Celexa and Vimovo drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Celexa (citalopram hydrobromide) and Vimovo (esomeprazole magnesium; naproxen). Common drug interactions include non-cardiac chest pain among females and chronic kidney disease among males.
The phase IV clinical study analyzes what interactions people have when they take Celexa and Vimovo. It is created by eHealthMe based on reports of 39 people who take the same drugs from the FDA, and is updated regularly.
What is Celexa?
Celexa has active ingredients of citalopram hydrobromide. It is often used in depression. eHealthMe is studying from 56,390 Celexa users. Check the latest studies of Celexa.
What is Vimovo?
Vimovo has active ingredients of esomeprazole magnesium; naproxen. It is often used in osteoarthritis. eHealthMe is studying from 9,608 Vimovo users. Check the latest studies of Vimovo.
eHealthMe: drug outcomes in the real world
eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.
39 people who take Celexa and Vimovo together, and have interactions are studied.

What are the common drug interactions of Celexa and Vimovo, by gender? *:
female:
- Non-cardiac chest pain
- Pain in jaw
- Parathyroid tumour benign (parathyroid tumour non-cancerous)
- Procedural headache
- Psoriasis (immune-mediated disease that affects the skin)
- Retching (strong involuntary effort to vomit)
- Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
- Spinal pain (pain in spine)
- Suicidal ideation
- Therapeutic response unexpected
male:
- Chronic kidney disease
- Renal failure (kidney dysfunction)
- Chest discomfort
- Chills (felling of cold)
- Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
- Dizziness
- Drug ineffective
- Dyspepsia (indigestion)
- Fibromyalgia (a long-term condition which causes pain all over the body)
- Hyperhidrosis (abnormally increased sweating)
What are the common drug interactions of Celexa and Vimovo, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Cholecystitis (infection of gallbladder)
- Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
- Gallbladder disorder
40-49:
- Chronic kidney disease
- Renal failure (kidney dysfunction)
- Renal injury (kidney injury)
- Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
- Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
- Arthralgia (joint pain)
- Fatigue (feeling of tiredness)
- Influenza
- Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
- Pleural effusion (water on the lungs)
50-59:
- Arthralgia (joint pain)
- Chest discomfort
- Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
- Dyspnoea (difficult or laboured respiration)
- Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
- Pulmonary sarcoidosis (growth of tiny collections of inflammatory cells in lungs)
- Respiratory tract congestion (blockage on respiratory system)
- Throat irritation
- Abnormal dreams
- Asthenia (weakness)
60+:
- Malaise (a feeling of general discomfort or uneasiness)
- Acne (skin problems that cause pimples)
- Lymphadenopathy (disease or enlargement of lymph nodes)
- Mouth ulceration (mouth ulcers)
- Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)
- Nail disorder (disease of nail)
- Night sweats (sweating in night)
- Pneumonia
- Pulmonary fibrosis (formation or development of excess fibrous connective tissue (fibrosis) in the lungs)
- Pyrexia (fever)
What are the existing conditions these people have? *
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 11 people, 28.21%
- Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 9 people, 23.08%
- Pain: 7 people, 17.95%
- Stress And Anxiety: 5 people, 12.82%
- High Blood Pressure: 5 people, 12.82%
- Arthritis (form of joint disorder that involves inflammation of one or more joints): 5 people, 12.82%
- Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 4 people, 10.26%
- Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 3 people, 7.69%
- Multiple Allergies (allergy to multiple agents): 3 people, 7.69%
- Insomnia (sleeplessness): 3 people, 7.69%
* Approximation only. Some reports may have incomplete information.
Do you take Celexa and Vimovo?
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Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Celexa and Vimovo:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Celexa:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Vimovo:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Celexa and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Vimovo and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Hosseini, S. H., & Ahmadi, A., "Peripheral edema occurring during treatment with risperidone combined with citalopram", Case reports in medicine, 2012 Jan .
- Hosseini, S. H., & Ahmadi, A., "Peripheral edema occurring during treatment with risperidone combined with citalopram", Case reports in medicine, 2012 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on citalopram hydrobromide and esomeprazole magnesium; naproxen (the active ingredients of Celexa and Vimovo, respectively), and Celexa and Vimovo (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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