Celexa and Zonisamide drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Celexa (citalopram hydrobromide) and Zonisamide (zonisamide). Common drug interactions include suicidal ideation among females and gait disturbance among males.

The phase IV clinical study analyzes what interactions people have when they take Celexa and Zonisamide. It is created by eHealthMe based on reports of 62 people who take the same drugs from the FDA, and is updated regularly.

What is Celexa?

Celexa has active ingredients of citalopram hydrobromide. It is often used in depression. eHealthMe is studying from 56,390 Celexa users. Check the latest studies of Celexa.

What is Zonisamide?

Zonisamide has active ingredients of zonisamide. It is often used in epilepsy. eHealthMe is studying from 11,445 Zonisamide users. Check the latest studies of Zonisamide.

On Jul, 26, 2026

62 people who take Celexa and Zonisamide together, and have interactions are studied.

Celexa and Zonisamide drug interactions.

What are the common drug interactions of Celexa and Zonisamide, by gender? *:

female:

Suicidal ideation
Fatigue (feeling of tiredness)
Dizziness
Oxygen consumption increased
Post-traumatic stress disorder
Status epilepticus (a life-threatening condition in which the brain is in a state of persistent seizure)
Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection)
Abdominal distension
Abnormal faeces (abnormal stool)
Fluid retention (an abnormal accumulation of fluid in the blood)

male:

Gait disturbance
Spinal fusion surgery
Oedema peripheral (superficial swelling)
Spinal disorder (disease of spine a back bone)

What are the common drug interactions of Celexa and Zonisamide, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Abdominal pain
Anuria (failure of the kidneys to produce urine)
Coma (state of unconsciousness lasting more than six hours)
Pregnancy
Pulseless electrical activity
Uterine hypertonus (hypertonic uterine dysfunction is a potential complication of labor induction)

30-39:

Weight increased
Adenomyosis (presence of ectopic glandular tissue found in muscle)
Dyspareunia (painful sexual intercourse)
Glaucoma (increased fluid pressure in the eye with vision loss)
Pelvic pain
Rectocele (a bulging of the front wall of the rectum into the back wall of the vagina)
Stress urinary incontinence (leak urine with things like coughing, sneezing or exercise)
Urethral disorder
Serotonin syndrome (occurs when two drugs that affect the body's level of serotonin are taken together at the same time)
Amenorrhoea (absence of a menstrual period in a woman of reproductive age)

40-49:

Abdominal pain
Back pain
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
Diarrhoea
Discomfort
Drug effect decreased
Drug ineffective
Dyspnoea (difficult or laboured respiration)
Faecaloma (hard mass of fecal matter)
Headache (pain in head)

50-59:

Post-traumatic stress disorder
Status epilepticus (a life-threatening condition in which the brain is in a state of persistent seizure)
Suicidal ideation
Histoplasmosis disseminated (respiratory infection caused by inhaling the spores of the fungus histoplasma capsulatum)
Lymphadenitis (inflammation or enlargement of a lymph node)
Aphasia (damage to the parts of the brain that control language)
Lymphadenitis fungal (fungal infection of lymph nodes)
Psychotic disorder
Staring (a prolonged gaze or fixed look)
Chills (felling of cold)

60+:

Pneumonia
Oedema (fluid collection in tissue)
Fatigue (feeling of tiredness)
Fluid retention (an abnormal accumulation of fluid in the blood)
Infusion site discolouration
Infusion site erythema (reddening of the skin at infusion site)
Infusion site haematoma (localized swelling filled with blood at infusion site)
Infusion site induration
Infusion site mass
Infusion site pain

What are the existing conditions these people have? *

Immunodeficiency Common Variable: 13 people, 20.97%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 11 people, 17.74%
Seizures (abnormal excessive or synchronous neuronal activity in the brain): 8 people, 12.90%
Idiopathic Generalised Epilepsy (epileptic disorders that are believed to have a strong underlying genetic basis): 5 people, 8.06%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 5 people, 8.06%
Pain: 4 people, 6.45%
Osteopenia (a condition where bone mineral density is lower than normal): 4 people, 6.45%
Neuralgia (pain in one or more nerves): 4 people, 6.45%
Multiple Allergies (allergy to multiple agents): 4 people, 6.45%
Hypertonic Bladder (bladder-storage function that causes a sudden urge to urinate): 4 people, 6.45%

* Approximation only. Some reports may have incomplete information.

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