Cellcept and Aciphex drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Cellcept (mycophenolate mofetil) and Aciphex (rabeprazole sodium). Common drug interactions include osteoporosis among females and renal failure among males.

The phase IV clinical study analyzes what interactions people have when they take Cellcept and Aciphex. It is created by eHealthMe based on reports of 80 people who take the same drugs from the FDA, and is updated regularly.

What is Cellcept?

Cellcept has active ingredients of mycophenolate mofetil. It is often used in systemic lupus erythematosus. eHealthMe is studying from 41,872 Cellcept users. Check the latest studies of Cellcept.

What is Aciphex?

Aciphex has active ingredients of rabeprazole sodium. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 25,301 Aciphex users. Check the latest studies of Aciphex.



On Jul, 10, 2026

80 people who take Cellcept and Aciphex together, and have interactions are studied.

Cellcept and Aciphex drug interactions.

What are the common drug interactions of Cellcept and Aciphex, by gender? *:

female:

  1. Osteoporosis (bones weak and more likely to break)
  2. Pleural effusion (water on the lungs)
  3. Pneumonia
  4. Rash papular (redness with papule)
  5. Skin exfoliation (removal of the oldest dead skin cells)
  6. Muscular weakness (muscle weakness)
  7. Rash
  8. Somnolence (a state of near-sleep, a strong desire for sleep)
  9. Ankle fracture
  10. Blood culture positive

male:

  1. Renal failure (kidney dysfunction)
  2. Chronic kidney disease
  3. Glaucoma (increased fluid pressure in the eye with vision loss)
  4. Metabolic encephalopathy (disorder or disease of the brain due to the body's disability to use energy)
  5. Retinal detachment (a disorder of the eye in which the retina peels away from its underlying layer of support tissue)
  6. Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
  7. Blood creatinine increased
  8. Renal failure chronic (long lasting kidney dysfunction)
  9. Abdominal pain
  10. Blindness

What are the common drug interactions of Cellcept and Aciphex, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

  1. Vomiting

10-19:

n/a

20-29:

  1. Abdominal distension
  2. Accident at home
  3. Adrenal atrophy (partial or complete wasting away of a adrenal gland)
  4. Adrenal insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids)
  5. Ankle fracture
  6. Body height decreased
  7. Burns third degree
  8. Chronic kidney disease
  9. Coeliac disease (simple food intolerance)
  10. Diarrhoea

30-39:

  1. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  2. Anxiety
  3. Back pain
  4. Emotional distress
  5. Gait disturbance
  6. Hyperkeratosis (thickening of the outer layer of the skin)
  7. Joint range of motion decreased (disease of joint movement)
  8. Muscle fatigue (a condition in which muscles cannot exert their normal force)
  9. Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
  10. Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)

40-49:

  1. Diarrhoea
  2. Renal failure (kidney dysfunction)
  3. Chronic kidney disease
  4. Dehydration (dryness resulting from the removal of water)
  5. Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
  6. Nephrogenic anaemia (anaemia due to kidney disease)
  7. Pyrexia (fever)
  8. Sinusitis (inflammation of sinus)
  9. Anxiety
  10. Chills (felling of cold)

50-59:

  1. Road traffic accident
  2. Serum sickness (hypersensitivity reaction that results from the injection of heterologous or foreign protein or serum)
  3. Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
  4. Swelling
  5. Tinnitus (a ringing in the ears)
  6. Tooth loss
  7. Type 2 diabetes mellitus
  8. Vision blurred
  9. Visual acuity reduced (reduced clearness of vision)
  10. Visual field defect

60+:

  1. Chronic kidney disease
  2. Contusion (a type of hematoma of tissue in which capillaries)
  3. Headache (pain in head)
  4. Vomiting
  5. Anaemia (lack of blood)
  6. Bacterial infection
  7. Blood culture positive
  8. Citrobacter infection (infection by citrobacter (bacteria))
  9. Decreased appetite
  10. Enterococcal infection

What are the existing conditions these people have? *

  1. High Blood Pressure: 15 people, 18.75%
  2. Pain: 15 people, 18.75%
  3. High Blood Cholesterol: 10 people, 12.50%
  4. Diabetes: 8 people, 10.00%
  5. Hepatitis C: 8 people, 10.00%
  6. Anaemia (lack of blood): 8 people, 10.00%
  7. Hypersensitivity: 7 people, 8.75%
  8. Cardiac Disorder: 7 people, 8.75%
  9. Nausea (feeling of having an urge to vomit): 6 people, 7.50%
  10. Stress And Anxiety: 6 people, 7.50%

* Approximation only. Some reports may have incomplete information.

Do you take Cellcept and Aciphex?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Cellcept and Aciphex:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Cellcept:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Aciphex:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Cellcept and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Aciphex and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on mycophenolate mofetil and rabeprazole sodium (the active ingredients of Cellcept and Aciphex, respectively), and Cellcept and Aciphex (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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