Cellcept and Megestrol acetate drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Cellcept (mycophenolate mofetil) and Megestrol acetate (megestrol acetate). Common drug interactions include chronic graft versus host disease among females and anxiety among males.

The phase IV clinical study analyzes what interactions people have when they take Cellcept and Megestrol acetate. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.

What is Cellcept?

Cellcept has active ingredients of mycophenolate mofetil. It is often used in systemic lupus erythematosus. eHealthMe is studying from 41,872 Cellcept users. Check the latest studies of Cellcept.

What is Megestrol acetate?

Megestrol acetate has active ingredients of megestrol acetate. It is often used in appetite - decreased. eHealthMe is studying from 5,427 Megestrol acetate users. Check the latest studies of Megestrol acetate.



On Aug, 03, 2026

14 people who take Cellcept and Megestrol acetate together, and have interactions are studied.

Cellcept and Megestrol acetate drug interactions.

What are the common drug interactions of Cellcept and Megestrol Acetate, by gender? *:

female:

  1. Chronic graft versus host disease (immune cells attack the host's body cells after transplant)
  2. Chronic lymphocytic leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell))
  3. Colitis (inflammation of colon)
  4. Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)
  5. Diarrhoea
  6. Diffuse large b-cell lymphoma (cancer of b cells, a type of white blood cell)
  7. Dry mouth
  8. Ecchymosis (a discoloration of the skin resulting from bleeding underneath)
  9. Epistaxis (bleed from the nose)
  10. Febrile neutropenia (fever with reduced white blood cells)

male:

  1. Anxiety
  2. Fatigue (feeling of tiredness)
  3. Foot deformity (functional disability of foot)
  4. Gait disturbance
  5. General physical health deterioration (weak health status)
  6. Hypoaesthesia (reduced sense of touch or sensation)
  7. Joint contracture (a permanent shortening of a muscle or joint)
  8. Joint range of motion decreased (disease of joint movement)
  9. Mobility decreased (ability to move is reduced)
  10. Muscle atrophy (a decrease in the mass of the muscle)

What are the common drug interactions of Cellcept and Megestrol Acetate, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  2. Anxiety
  3. Arthralgia (joint pain)
  4. Balance disorder
  5. Dysstasia (difficulty in standing)
  6. Emotional distress
  7. Erythema (redness of the skin)
  8. Fatigue (feeling of tiredness)
  9. Fibrosis (formation of excess fibrous connective tissue in an organ or tissue)
  10. Foot deformity (functional disability of foot)

30-39:

n/a

40-49:

  1. Skin tightness
  2. Erythema (redness of the skin)
  3. Exfoliative rash (scaly red generalized skin rash)
  4. Fibrosis (formation of excess fibrous connective tissue in an organ or tissue)
  5. Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)
  6. Oedema peripheral (superficial swelling)
  7. Skin hyperpigmentation (disorders affect the colour of your skin)
  8. Skin hypertrophy (skin cells enlarges)
  9. Skin induration (an abnormally hard spot or area on the skin)
  10. Atrophy (wasting away of a part of the body)

50-59:

  1. Abdominal mass (localized enlargement or swelling in the human abdomen)
  2. Abdominal pain
  3. Aphthous ulcer (mouth ulcer)
  4. Bacterial sepsis
  5. Catheter site haematoma (blood clot at catheter site)
  6. Chronic graft versus host disease (immune cells attack the host's body cells after transplant)
  7. Chronic lymphocytic leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell))
  8. Colitis (inflammation of colon)
  9. Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)
  10. Diarrhoea

60+:

  1. Aggression
  2. Anaemia (lack of blood)
  3. Cough
  4. Diarrhoea
  5. Dizziness
  6. Dyspnoea (difficult or laboured respiration)
  7. Failure to thrive (inadequate weight gain and physical growth in children)
  8. Fall
  9. Fatigue (feeling of tiredness)
  10. Hypertension (high blood pressure)

What are the existing conditions these people have? *

  1. Nuclear Magnetic Resonance Imaging Abdominal: 7 people, 50.00%
  2. Pain: 6 people, 42.86%
  3. Nuclear Magnetic Resonance Imaging Brain: 6 people, 42.86%
  4. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 4 people, 28.57%
  5. Urination - Excessive At Night: 2 people, 14.29%
  6. Loss Of Consciousness: 2 people, 14.29%
  7. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 2 people, 14.29%
  8. Autonomic Neuropathy (malfunction of the autonomic nervous system (ans)): 2 people, 14.29%
  9. Complications Of Transplanted Lung: 2 people, 14.29%
  10. Constipation: 2 people, 14.29%

* Approximation only. Some reports may have incomplete information.

Do you take Cellcept and Megestrol acetate?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Cellcept and Megestrol acetate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Cellcept:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Megestrol acetate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Cellcept and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Megestrol acetate and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on mycophenolate mofetil and megestrol acetate (the active ingredients of Cellcept and Megestrol acetate, respectively), and Cellcept and Megestrol acetate (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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