Cellcept and Novantrone drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Cellcept (mycophenolate mofetil) and Novantrone (mitoxantrone hydrochloride). Common drug interactions include acute promyelocytic leukaemia among females and pancreatic carcinoma among males.

The phase IV clinical study analyzes what interactions people have when they take Cellcept and Novantrone. It is created by eHealthMe based on reports of 23 people who take the same drugs from the FDA, and is updated regularly.

What is Cellcept?

Cellcept has active ingredients of mycophenolate mofetil. It is often used in systemic lupus erythematosus. eHealthMe is studying from 41,872 Cellcept users. Check the latest studies of Cellcept.

What is Novantrone?

Novantrone has active ingredients of mitoxantrone hydrochloride. It is often used in multiple sclerosis. eHealthMe is studying from 3,349 Novantrone users. Check the latest studies of Novantrone.



On Jul, 11, 2026

23 people who take Cellcept and Novantrone together, and have interactions are studied.

Cellcept and Novantrone drug interactions.

What are the common drug interactions of Cellcept and Novantrone, by gender? *:

female:

  1. Acute promyelocytic leukaemia (cancer of the blood and bone marrow)
  2. Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
  3. Atrophy (wasting away of a part of the body)
  4. Blindness cortical
  5. Confusional state
  6. Disorientation (disability in which the senses of time, direction, and recognition of people and places)
  7. Faecal incontinence (a lack of control over passing stool)
  8. Myelitis transverse (a neurological condition consisting of an inflammatory process of the spinal cord)
  9. Neurogenic bladder (the normal function of the bladder is to store and empty urine in a coordinated, controlled fashion)
  10. Optic atrophy (the loss of a proportion of optic disc nerve fibres)

male:

  1. Pancreatic carcinoma (pancreatic cancer)
  2. Infection
  3. Activated partial thromboplastin time prolonged
  4. Amyotrophy (muscular wasting or atrophy)
  5. Anxiety
  6. Asthenia (weakness)
  7. Balance disorder
  8. Basal cell carcinoma (a skin cancer, it rarely metastasizes or kills)
  9. Cancer pain
  10. Candidiasis (candidiasis or thrush is a fungal infection)

What are the common drug interactions of Cellcept and Novantrone, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Graft versus host disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body)
  2. Infection
  3. Respiratory failure (inadequate gas exchange by the respiratory system)
  4. Venoocclusive liver disease (small veins in the liver are obstructed)
  5. Cytomegalovirus viraemia (cytomegalo virus in blood stream)
  6. Hyperuricaemia (level of uric acid in the blood that is abnormally high)
  7. Renal impairment (severely reduced kidney function)
  8. Thrombotic microangiopathy (a pathology that results in thrombosis in capillaries and arterioles, due to an endothelial injury)

30-39:

  1. Progressive multiple sclerosis (chronic autoimmune disease of the central nervous system in which gradual destruction of myelin occurs in patches throughout the brain or spinal cord)
  2. Skin cancer
  3. Basal cell carcinoma (a skin cancer, it rarely metastasizes or kills)
  4. Brain stem haemorrhage (bleeding into structures of brain stem)
  5. Cerebral haemorrhage (bleeding within the brain)

40-49:

  1. Acute promyelocytic leukaemia (cancer of the blood and bone marrow)
  2. Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
  3. Bladder disorder
  4. Blood iron increased
  5. Eye pain
  6. Haemorrhoidal haemorrhage (bleeding from the haemorrhoids)
  7. Oedema peripheral (superficial swelling)

50-59:

  1. Amyotrophy (muscular wasting or atrophy)
  2. Asthenia (weakness)
  3. Balance disorder
  4. Candidiasis (candidiasis or thrush is a fungal infection)
  5. Citrobacter infection (infection by citrobacter (bacteria))
  6. Cytomegalovirus infection
  7. Gait disturbance
  8. Grand mal convulsion (a type of generalized seizure that affects the entire brain)
  9. Hyperthyroidism (over activity of the thyroid gland)
  10. Infection

60+:

  1. Pancreatic carcinoma (pancreatic cancer)
  2. Acute graft versus host disease (acute complication following an allogeneic tissue/blood transplant)
  3. Disseminated intravascular coagulation (systemic activation of blood coagulation)
  4. Dyspnoea (difficult or laboured respiration)
  5. Haematocrit decreased
  6. Haemoglobin decreased
  7. Hypotension (abnormally low blood pressure)
  8. International normalised ratio increased
  9. Neutropenia (an abnormally low number of neutrophils)
  10. Renal failure acute (rapid kidney dysfunction)

What are the existing conditions these people have? *

  1. Immunodeficiency Disorders: 4 people, 17.39%

* Approximation only. Some reports may have incomplete information.

Do you take Cellcept and Novantrone?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Cellcept and Novantrone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Cellcept:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Novantrone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Cellcept and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Novantrone and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on mycophenolate mofetil and mitoxantrone hydrochloride (the active ingredients of Cellcept and Novantrone, respectively), and Cellcept and Novantrone (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: