Cellcept and Primaxin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Cellcept (mycophenolate mofetil) and Primaxin (cilastatin sodium; imipenem). Common drug interactions include mucosal inflammation among females and hepatic artery stenosis among males.

The phase IV clinical study analyzes what interactions people have when they take Cellcept and Primaxin. It is created by eHealthMe based on reports of 26 people who take the same drugs from the FDA, and is updated regularly.

What is Cellcept?

Cellcept has active ingredients of mycophenolate mofetil. It is often used in systemic lupus erythematosus. eHealthMe is studying from 41,872 Cellcept users. Check the latest studies of Cellcept.

What is Primaxin?

Primaxin has active ingredients of cilastatin sodium; imipenem. eHealthMe is studying from 4,540 Primaxin users. Check the latest studies of Primaxin.



On Jul, 12, 2026

26 people who take Cellcept and Primaxin together, and have interactions are studied.

Cellcept and Primaxin drug interactions.

What are the common drug interactions of Cellcept and Primaxin, by gender? *:

female:

  1. Mucosal inflammation (infection of mucous membrane)
  2. Rash
  3. Toxic epidermal necrolysis (a rare, life-threatening skin condition that is usually caused by a reaction to drugs causes wide spread skin destruction)
  4. Blood creatinine increased
  5. Hepatic failure (liver failure)
  6. Lower respiratory tract infection
  7. Post procedural complication
  8. Renal failure (kidney dysfunction)
  9. Thrombocytopenia (decrease of platelets in blood)

male:

  1. Hepatic artery stenosis (the abnormal narrowing of a hepatic artery)
  2. Pleural effusion (water on the lungs)
  3. Enterococcal infection
  4. Sepsis (a severe blood infection that can lead to organ failure and death)
  5. Thrombocytopenia (decrease of platelets in blood)
  6. Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)
  7. Biliary anastomosis complication (complication of biliary-enteric anastomosis (bea) is a common surgical procedure)
  8. Bronchopneumonia (inflammation of the lungs, arising in the bronchi or bronchioles)
  9. Cholangitis (infection of the bile duct)
  10. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)

What are the common drug interactions of Cellcept and Primaxin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

  1. Abdominal pain
  2. Blood creatinine increased
  3. Blood triglycerides increased
  4. Diarrhoea
  5. Gamma-glutamyltransferase increased
  6. Lower respiratory tract infection
  7. Pancreatitis (inflammation of pancreas)
  8. Pneumoperitoneum (air or gas in the abdominal (peritoneal) cavity)

10-19:

  1. Bone marrow transplant rejection

20-29:

  1. Hepatic failure (liver failure)
  2. Post procedural complication
  3. Renal failure (kidney dysfunction)

30-39:

  1. Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)
  2. Haemoglobin decreased
  3. Pyrexia (fever)
  4. Thrombocytopenia (decrease of platelets in blood)
  5. White blood cell count decreased

40-49:

  1. Thrombocytopenia (decrease of platelets in blood)
  2. Blood creatinine increased
  3. Septic shock (shock due to blood infection)

50-59:

  1. Cholestasis (a condition where bile cannot flow from the liver to the duodenum)
  2. Blood bilirubin increased
  3. Diarrhoea
  4. Enterococcal infection
  5. Inflammation
  6. Transplant rejection (a transplant material is not worked)
  7. Deafness
  8. Seizure (abnormal excessive or synchronous neuronal activity in the brain)
  9. Acute respiratory failure
  10. Biliary anastomosis complication (complication of biliary-enteric anastomosis (bea) is a common surgical procedure)

60+:

  1. Mucosal inflammation (infection of mucous membrane)
  2. Rash
  3. Toxic epidermal necrolysis (a rare, life-threatening skin condition that is usually caused by a reaction to drugs causes wide spread skin destruction)
  4. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
  5. Gastrointestinal infection (infection of stomach and intestine)
  6. Multi-organ failure (multisystem organ failure)
  7. Polyomavirus-associated nephropathy (polyomavirus-associated kidney disease)
  8. Urinary tract infection

What are the existing conditions these people have? *

  1. Inflammation: 4 people, 15.38%
  2. Hyperuricaemia (level of uric acid in the blood that is abnormally high): 4 people, 15.38%
  3. Blood Bilirubin Increased: 4 people, 15.38%
  4. Infection: 3 people, 11.54%
  5. Transplant Rejection (a transplant material is not worked): 2 people, 7.69%
  6. Pain: 2 people, 7.69%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Cellcept and Primaxin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Cellcept:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Primaxin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Cellcept and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Primaxin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on mycophenolate mofetil and cilastatin sodium; imipenem (the active ingredients of Cellcept and Primaxin, respectively), and Cellcept and Primaxin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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