Centrum silver and Cimzia drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Centrum silver (ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e) and Cimzia (certolizumab pegol). Common drug interactions include drug ineffective among females and pain among males.

The phase IV clinical study analyzes what interactions people have when they take Centrum silver and Cimzia. It is created by eHealthMe based on reports of 46 people who take the same drugs from the FDA, and is updated regularly.

What is Centrum silver?

Centrum silver has active ingredients of ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e. It is often used in vitamin supplementation. eHealthMe is studying from 19,997 Centrum silver users. Check the latest studies of Centrum silver.

What is Cimzia?

Cimzia has active ingredients of certolizumab pegol. It is often used in rheumatoid arthritis. eHealthMe is studying from 106,745 Cimzia users. Check the latest studies of Cimzia.



On Jul, 10, 2026

46 people who take Centrum silver and Cimzia together, and have interactions are studied.

Centrum silver and Cimzia drug interactions.

What are the common drug interactions of Centrum Silver and Cimzia, by gender? *:

female:

  1. Drug ineffective
  2. Alopecia (absence of hair from areas of the body)
  3. Rash
  4. Arthralgia (joint pain)
  5. Injection site bruising
  6. Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
  7. Abdominal discomfort
  8. Chills (felling of cold)
  9. Diarrhoea
  10. Dry skin

male:

  1. Pain
  2. Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
  3. Sinusitis (inflammation of sinus)
  4. Tendonitis (a condition that causes pain and swelling of tendons)
  5. Abscess (pus)
  6. Fistula (an abnormal connection or passageway between two)
  7. Psoriasis (immune-mediated disease that affects the skin)
  8. Cellulitis (infection under the skin)
  9. Death
  10. Histoplasmosis disseminated (respiratory infection caused by inhaling the spores of the fungus histoplasma capsulatum)

What are the common drug interactions of Centrum Silver and Cimzia, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Depression
  2. Knee arthroplasty
  3. Post procedural infection
  4. Suicidal ideation

50-59:

  1. Influenza
  2. Pain
  3. Pain in extremity
  4. Sinusitis (inflammation of sinus)
  5. Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
  6. Carpal tunnel syndrome (nerve compression at wrist results numbness weakness, pain , swelling)
  7. Cellulitis (infection under the skin)
  8. Cholecystitis (infection of gallbladder)
  9. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  10. Histoplasmosis disseminated (respiratory infection caused by inhaling the spores of the fungus histoplasma capsulatum)

60+:

  1. Alopecia (absence of hair from areas of the body)
  2. Psoriasis (immune-mediated disease that affects the skin)
  3. Abdominal pain lower
  4. Abdominal pain upper
  5. Asthenia (weakness)
  6. Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
  7. Chronic lymphocytic leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell))
  8. Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
  9. Colitis ischaemic (due to infection of intestine impaired blood supply to colon)
  10. Flatulence (flatus expelled through the anus)

What are the existing conditions these people have? *

  1. Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 16 people, 34.78%
  2. Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 6 people, 13.04%
  3. Osteoporosis (bones weak and more likely to break): 3 people, 6.52%
  4. High Blood Pressure: 3 people, 6.52%

* Approximation only. Some reports may have incomplete information.

Do you take Centrum silver and Cimzia?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Centrum silver and Cimzia:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Centrum silver:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Cimzia:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Centrum silver and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Cimzia and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e and certolizumab pegol (the active ingredients of Centrum silver and Cimzia, respectively), and Centrum silver and Cimzia (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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