Centrum silver and Urocit-k drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Centrum silver (ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e) and Urocit-k (potassium citrate). Common drug interactions include cardiac failure congestive among females and clostridium difficile colitis among males.

The phase IV clinical study analyzes what interactions people have when they take Centrum silver and Urocit-k. It is created by eHealthMe based on reports of 35 people who take the same drugs from the FDA, and is updated regularly.

What is Centrum silver?

Centrum silver has active ingredients of ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e. It is often used in vitamin supplementation. eHealthMe is studying from 19,997 Centrum silver users. Check the latest studies of Centrum silver.

What is Urocit-k?

Urocit-k has active ingredients of potassium citrate. It is often used in kidney stones. eHealthMe is studying from 708 Urocit-k users. Check the latest studies of Urocit-k.



On Jul, 09, 2026

35 people who take Centrum silver and Urocit-k together, and have interactions are studied.

Centrum silver and Urocit-k drug interactions.

What are the common drug interactions of Centrum Silver and Urocit-K, by gender? *:

female:

  1. Cardiac failure congestive
  2. Intervertebral disc operation
  3. Weight decreased
  4. Chondromalacia (anterior knee pain due to irritation of the cartilage on the under surface of the kneecap)
  5. Deformity (disfigurement)
  6. Dizziness
  7. Dry mouth
  8. Emotional distress
  9. Eye infection
  10. Eye pain

male:

  1. Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection)
  2. Confusional state
  3. Dysuria (painful or difficult urination)
  4. Migraine (headache)
  5. Muscle spasms (muscle contraction)
  6. Neck pain
  7. Systemic inflammatory response syndrome (an inflammatory state affecting the whole body, frequently a response of the immune system to infection)

What are the common drug interactions of Centrum Silver and Urocit-K, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Emotional distress
  2. Eye infection
  3. Eye pain
  4. Facial bones fracture (bone fracture of face)
  5. Fall
  6. Femur fracture
  7. Glossitis (infection of tongue with soreness)
  8. Groin pain
  9. Haemolytic anaemia (anaemia due to haemolysis)
  10. Hand fracture

60+:

  1. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  2. Pulmonary embolism (blockage of the main artery of the lung)
  3. Anxiety
  4. Arrhythmia (irregular heartbeat)
  5. Arthralgia (joint pain)
  6. Bedridden
  7. Bone disorder
  8. Bone pain
  9. Breast cancer recurrent
  10. Bruxism (habitual grinding of the teeth, typically during sleep)

What are the existing conditions these people have? *

  1. Multiple Myeloma (cancer of the plasma cells): 5 people, 14.29%
  2. High Blood Pressure: 4 people, 11.43%
  3. Breast Cancer: 3 people, 8.57%
  4. Type 2 Diabetes: 2 people, 5.71%
  5. Transient Ischaemic Attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow)): 2 people, 5.71%
  6. Prostate Cancer Metastatic: 2 people, 5.71%
  7. Osteoporosis (bones weak and more likely to break): 2 people, 5.71%
  8. Metastases To Bone (cancer spreads to bone): 2 people, 5.71%
  9. Hyperlipidaemia (presence of excess lipids in the blood): 2 people, 5.71%
  10. Gout (uric acid crystals building up in the body): 2 people, 5.71%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Centrum silver and Urocit-k:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Centrum silver:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Urocit-k:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Centrum silver and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Urocit-k and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e and potassium citrate (the active ingredients of Centrum silver and Urocit-k, respectively), and Centrum silver and Urocit-k (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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