Centrum and Fentanyl-100 drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Centrum (ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e) and Fentanyl-100 (fentanyl). Common drug interactions include pain in jaw among females and ascites among males.

The phase IV clinical study analyzes what interactions people have when they take Centrum and Fentanyl-100. It is created by eHealthMe based on reports of 27 people who take the same drugs from the FDA, and is updated regularly.

What is Centrum?

Centrum has active ingredients of ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e. It is often used in vitamin supplementation. eHealthMe is studying from 34,686 Centrum users. Check the latest studies of Centrum.

What is Fentanyl-100?

Fentanyl-100 has active ingredients of fentanyl. It is often used in pain. eHealthMe is studying from 7,047 Fentanyl-100 users. Check the latest studies of Fentanyl-100.



On Jul, 26, 2026

27 people who take Centrum and Fentanyl-100 together, and have interactions are studied.

Centrum and Fentanyl-100 drug interactions.

What are the common drug interactions of Centrum and Fentanyl-100, by gender? *:

female:

  1. Pain in jaw
  2. Bone disorder
  3. Chondromalacia (anterior knee pain due to irritation of the cartilage on the under surface of the kneecap)
  4. Deformity (disfigurement)
  5. Dry mouth
  6. Dysphagia (a condition in which swallowing is difficult or painful)
  7. Eye infection
  8. Eye pain
  9. Facial bones fracture (bone fracture of face)
  10. Fall

male:

  1. Ascites (accumulation of fluid in the abdominal cavity)
  2. Pneumonia
  3. Gastric perforation (hole in stomach)
  4. Haematemesis (vomiting of blood)
  5. Hiatus hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm)
  6. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
  7. Pleural effusion (water on the lungs)
  8. Pyrexia (fever)
  9. Renal failure chronic (long lasting kidney dysfunction)
  10. Anxiety

What are the common drug interactions of Centrum and Fentanyl-100, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Renal failure acute (rapid kidney dysfunction)
  2. Abdominal distension
  3. Anaemia (lack of blood)
  4. Ascites (accumulation of fluid in the abdominal cavity)
  5. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  6. Blood creatinine increased
  7. Blood lactate dehydrogenase increased
  8. Blood pressure decreased
  9. Bone marrow failure
  10. Bundle branch block right (absence of transmission of electric impulses from the atrioventricular (av) bundle of his to the right ventricle)

50-59:

  1. Facial bones fracture (bone fracture of face)
  2. Fall
  3. Haemolytic anaemia (anaemia due to haemolysis)
  4. Hand fracture
  5. Hiatus hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm)
  6. Hyperkeratosis (thickening of the outer layer of the skin)
  7. Hypoaesthesia (reduced sense of touch or sensation)
  8. Infection
  9. Injury
  10. Insomnia (sleeplessness)

60+:

  1. Drug ineffective
  2. Headache (pain in head)
  3. Arthralgia (joint pain)
  4. Cardiac failure congestive
  5. Cardiomegaly (increased size of heart than normal)
  6. Cystitis (inflammation of the wall of the bladder)
  7. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  8. Depression
  9. Infection
  10. Insomnia (sleeplessness)

What are the existing conditions these people have? *

  1. Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 6 people, 22.22%
  2. Back Pain: 5 people, 18.52%
  3. High Blood Cholesterol: 4 people, 14.81%
  4. Depression: 3 people, 11.11%
  5. Constipation: 3 people, 11.11%
  6. Sciatica (a set of symptoms including pain caused by general compression or irritation of one of five spinal nerve roots of each sciatic nerve): 2 people, 7.41%
  7. Muscle Spasms (muscle contraction): 2 people, 7.41%
  8. High Blood Pressure: 2 people, 7.41%
  9. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 7.41%
  10. Fluid Retention (an abnormal accumulation of fluid in the blood): 2 people, 7.41%

* Approximation only. Some reports may have incomplete information.

Do you take Centrum and Fentanyl-100?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Centrum and Fentanyl-100:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Centrum:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Fentanyl-100:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Centrum and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Fentanyl-100 and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e and fentanyl (the active ingredients of Centrum and Fentanyl-100, respectively), and Centrum and Fentanyl-100 (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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