Oxycontin and Lantus solostar drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Oxycontin (oxycodone hydrochloride) and Lantus solostar (insulin glargine recombinant). Common drug interactions include hypoaesthesia among females and blood glucose increased among males.

The phase IV clinical study analyzes what interactions people have when they take Oxycontin and Lantus solostar. It is created by eHealthMe based on reports of 44 people who take the same drugs from the FDA, and is updated regularly.

What is Oxycontin?

Oxycontin has active ingredients of oxycodone hydrochloride. It is often used in pain. eHealthMe is studying from 212,533 Oxycontin users. Check the latest studies of Oxycontin.

What is Lantus solostar?

Lantus solostar has active ingredients of insulin glargine recombinant. It is often used in diabetes. eHealthMe is studying from 41,639 Lantus solostar users. Check the latest studies of Lantus solostar.



On Jul, 26, 2026

44 people who take Oxycontin and Lantus solostar together, and have interactions are studied.

Oxycontin and Lantus solostar drug interactions.

What are the common drug interactions of Oxycontin and Lantus Solostar, by gender? *:

female:

  1. Hypoaesthesia (reduced sense of touch or sensation)
  2. Hypotension (abnormally low blood pressure)
  3. Immune system disorder
  4. Injection site pain
  5. Injection site pruritus (severe itching at injection site)
  6. Insomnia (sleeplessness)
  7. Low density lipoprotein increased (cholesterol increased in blood)
  8. Muscle spasms (muscle contraction)
  9. Neuropathy peripheral (surface nerve damage)
  10. Oedema peripheral (superficial swelling)

male:

  1. Blood glucose increased
  2. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  3. Muscle spasms (muscle contraction)
  4. Prostate cancer
  5. Skin fissures (a crack in the skin)
  6. Surgery
  7. Thyroid disorder (thyroid diseases)
  8. Compression fracture (fracture due to pressure caused by injury)
  9. Death
  10. Malaise (a feeling of general discomfort or uneasiness)

What are the common drug interactions of Oxycontin and Lantus Solostar, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Dizziness
  2. Drug ineffective
  3. Nausea (feeling of having an urge to vomit)

30-39:

n/a

40-49:

  1. Plasmacytoma (neoplasm of plasma cells (usually in bone marrow))
  2. Metastases to liver (cancer spreads to liver)
  3. Pancreatic carcinoma metastatic (pancreatic cancer- metastatic)

50-59:

  1. Carpal tunnel syndrome (nerve compression at wrist results numbness weakness, pain , swelling)
  2. Fatigue (feeling of tiredness)
  3. Fibromyalgia (a long-term condition which causes pain all over the body)
  4. Insulin-like growth factor increased
  5. Somnolence (a state of near-sleep, a strong desire for sleep)
  6. Tremor (trembling or shaking movements in one or more parts of your body)
  7. White blood cell count decreased
  8. Compression fracture (fracture due to pressure caused by injury)
  9. Plasma cell myeloma (cancer that begins in plasma cells)
  10. Renal cancer (cancer of kidney)

60+:

  1. Blood glucose increased
  2. Hypotension (abnormally low blood pressure)
  3. Pleural effusion (water on the lungs)
  4. Rash macular (small, flat red spots)
  5. Asthenia (weakness)
  6. Blood potassium increased
  7. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  8. Burning sensation
  9. Compression fracture (fracture due to pressure caused by injury)
  10. Confusional state

What are the existing conditions these people have? *

  1. Multiple Myeloma (cancer of the plasma cells): 12 people, 27.27%
  2. Type 2 Diabetes: 5 people, 11.36%
  3. Gout (uric acid crystals building up in the body): 5 people, 11.36%
  4. Thyroid Diseases: 4 people, 9.09%
  5. Infection: 4 people, 9.09%
  6. Haemorrhoids (a swollen vein or group of veins in the region of the anus): 4 people, 9.09%
  7. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 9.09%
  8. Blood Pressure Abnormal: 4 people, 9.09%
  9. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 3 people, 6.82%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Oxycontin and Lantus solostar:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Oxycontin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Lantus solostar:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Oxycontin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Lantus solostar and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on oxycodone hydrochloride and insulin glargine recombinant (the active ingredients of Oxycontin and Lantus solostar, respectively), and Oxycontin and Lantus solostar (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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