Centrum and Novorapid drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Centrum (ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e) and Novorapid (insulin aspart recombinant). Common drug interactions include headache among females and metastatic renal cell carcinoma among males.
The phase IV clinical study analyzes what interactions people have when they take Centrum and Novorapid. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.
What is Centrum?
Centrum has active ingredients of ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e. It is often used in vitamin supplementation. eHealthMe is studying from 34,686 Centrum users. Check the latest studies of Centrum.
What is Novorapid?
Novorapid has active ingredients of insulin aspart recombinant. It is often used in type 1 diabetes. eHealthMe is studying from 24,730 Novorapid users. Check the latest studies of Novorapid.
13 people who take Centrum and Novorapid together, and have interactions are studied.

What are the common drug interactions of Centrum and Novorapid, by gender? *:
female:
- Headache (pain in head)
- Hyperkalaemia (damage to or disease of the kidney)
- Malaise (a feeling of general discomfort or uneasiness)
- Nausea (feeling of having an urge to vomit)
- Renal impairment (severely reduced kidney function)
- Vomiting
- Fall
- Hyperhidrosis (abnormally increased sweating)
- Insomnia (sleeplessness)
- Memory impairment
male:
- Metastatic renal cell carcinoma (spreadable kidney cell tumour)
- General physical health deterioration (weak health status)
- Hyperkalaemia (damage to or disease of the kidney)
- Blood iron decreased
- Blood triglycerides increased
- Prostate cancer
What are the common drug interactions of Centrum and Novorapid, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Infective pulmonary exacerbation of cystic fibrosis (severe infective lung disease with production of abnormally thick mucus)
30-39:
n/a
40-49:
- General physical health deterioration (weak health status)
- Hyperkalaemia (damage to or disease of the kidney)
50-59:
n/a
60+:
- Metastatic renal cell carcinoma (spreadable kidney cell tumour)
- Dehydration (dryness resulting from the removal of water)
- Vomiting
- Fall
- Hyperhidrosis (abnormally increased sweating)
- Insomnia (sleeplessness)
- Arthralgia (joint pain)
- Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
- Blood glucose decreased
- Blood iron decreased
What are the existing conditions these people have? *
- Type 2 Diabetes: 6 people, 46.15%
- Thyroid Diseases: 2 people, 15.38%
- Stress And Anxiety: 2 people, 15.38%
- Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 2 people, 15.38%
- High Blood Pressure: 2 people, 15.38%
- Depression: 2 people, 15.38%
- Urinary Incontinence (inability to control the flow of urine and involuntary urination): 1 person, 7.69%
- Gastric Disorder (disease of stomach): 1 person, 7.69%
- Arrhythmias (irregular heartbeat): 1 person, 7.69%
- Blood Disorder: 1 person, 7.69%
* Approximation only. Some reports may have incomplete information.
Do you take Centrum and Novorapid?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Centrum and Novorapid:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Centrum:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Novorapid:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Centrum and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Novorapid and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e and insulin aspart recombinant (the active ingredients of Centrum and Novorapid, respectively), and Centrum and Novorapid (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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