Centrum and Rinvoq drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Centrum (ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e) and Rinvoq (upadacitinib). Common drug interactions include pneumonia among females and arthralgia among males.

The phase IV clinical study analyzes what interactions people have when they take Centrum and Rinvoq. It is created by eHealthMe based on reports of 19 people who take the same drugs from the FDA, and is updated regularly.

What is Centrum?

Centrum has active ingredients of ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e. It is often used in vitamin supplementation. eHealthMe is studying from 34,686 Centrum users. Check the latest studies of Centrum.

What is Rinvoq?

Rinvoq has active ingredients of upadacitinib. eHealthMe is studying from 47,375 Rinvoq users. Check the latest studies of Rinvoq.

On Jul, 06, 2026

19 people who take Centrum and Rinvoq together, and have interactions are studied.

What are the common drug interactions of Centrum and Rinvoq, by gender? *:

female:

Pneumonia
Upper limb fracture
Back pain
Neck pain
Rheumatoid arthritis (a chronic progressive disease causing inflammation in the joints)
Air embolism
Asthma
Bladder prolapse (bulging of one or more of the pelvic organs into the vagina)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Drug ineffective

male:

Arthralgia (joint pain)
Cough
Pain
Peripheral swelling
Skin ulcer
Upper-airway cough syndrome

What are the common drug interactions of Centrum and Rinvoq, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Foot deformity (functional disability of foot)
Mobility decreased (ability to move is reduced)

40-49:

n/a

50-59:

Air embolism
Asthma
Bladder prolapse (bulging of one or more of the pelvic organs into the vagina)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Headache (pain in head)
Oxygen saturation decreased
Pneumonia
Arthralgia (joint pain)
Forearm fracture (fracture in between wrist to elbow)
Lower limb fracture

60+:

Arthralgia (joint pain)
Pain
Swelling
Upper limb fracture
Wrist fracture
Asthenia (weakness)
Balance disorder
Cardiomegaly (increased size of heart than normal)
Cough
Hypertension (high blood pressure)

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 16 people, 84.21%
Pain: 4 people, 21.05%
Swelling: 2 people, 10.53%
Stomatitis (inflammation of mucous membrane of mouth): 2 people, 10.53%
Sleep Disorder: 2 people, 10.53%
Gastric Disorder (disease of stomach): 2 people, 10.53%
High Blood Cholesterol: 2 people, 10.53%
Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 1 person, 5.26%
Hair Disorder: 1 person, 5.26%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 5.26%

* Approximation only. Some reports may have incomplete information.

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