Centrum and Tresiba drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Centrum (ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e) and Tresiba (insulin degludec). Common drug interactions include feeding disorder among females and cardiac failure congestive among males.

The phase IV clinical study analyzes what interactions people have when they take Centrum and Tresiba. It is created by eHealthMe based on reports of 59 people who take the same drugs from the FDA, and is updated regularly.

What is Centrum?

Centrum has active ingredients of ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e. It is often used in vitamin supplementation. eHealthMe is studying from 34,686 Centrum users. Check the latest studies of Centrum.

What is Tresiba?

Tresiba has active ingredients of insulin degludec. It is often used in type 1 diabetes. eHealthMe is studying from 20,677 Tresiba users. Check the latest studies of Tresiba.

On Jul, 06, 2026

59 people who take Centrum and Tresiba together, and have interactions are studied.

What are the common drug interactions of Centrum and Tresiba, by gender? *:

female:

Feeding disorder (when children refuse to eat certain food groups)
Foot fracture
Gastrointestinal disorder (functional problems of gastrointestinal tract)
Hallucination (an experience involving the perception of something not present)
Hand fracture
Injection site bruising
Injection site haemorrhage (bleeding from injection site)
Injection site pain
Intestinal obstruction
Intestinal ulcer

male:

Cardiac failure congestive
Influenza
Myocarditis (inflammation of heart muscle myocardium)
Nephrogenic anaemia (anaemia due to kidney disease)
Renal failure (kidney dysfunction)
Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
Abdominal pain
Arthralgia (joint pain)
Ascites (accumulation of fluid in the abdominal cavity)
Asthenia (weakness)

What are the common drug interactions of Centrum and Tresiba, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Cystic fibrosis (disease of the secretary glands)
Lung disorder (lung disease)

30-39:

n/a

40-49:

n/a

50-59:

Cardiac failure congestive
Influenza
Pain
Bell's palsy (facial paralysis)
Blood glucose increased
Chronic kidney disease
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Normal pressure hydrocephalus (a neurological disorder in which there is too much cerebrospinal fluid in the ventricles of the brain)
Oral candidiasis (fungal infection of mouth)
Renal failure (kidney dysfunction)

60+:

Urinary tract infection
Fall
Renal failure (kidney dysfunction)
Dyspnoea (difficult or laboured respiration)
Lung disorder (lung disease)
Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
Renal infarct (kidney damage due to lack of blood supply)
Thrombosis (formation of a blood clot inside a blood vessel)
Cardiac failure
Chronic kidney disease

What are the existing conditions these people have? *

Diabetes: 12 people, 20.34%
High Blood Pressure: 12 people, 20.34%
Pain: 10 people, 16.95%
High Blood Cholesterol: 9 people, 15.25%
Type 2 Diabetes: 9 people, 15.25%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 8 people, 13.56%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 6 people, 10.17%
Blood Pressure Abnormal: 6 people, 10.17%
Chest Pain: 6 people, 10.17%
Fluid Imbalance (imbalance of fluid in body in intake and fluid lost): 4 people, 6.78%

* Approximation only. Some reports may have incomplete information.

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