Centrum and Xalkori drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Centrum (ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e) and Xalkori (crizotinib). Common drug interactions include cough among females and eye disorder among males.

The phase IV clinical study analyzes what interactions people have when they take Centrum and Xalkori. It is created by eHealthMe based on reports of 21 people who take the same drugs from the FDA, and is updated regularly.

What is Centrum?

Centrum has active ingredients of ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e. It is often used in vitamin supplementation. eHealthMe is studying from 34,686 Centrum users. Check the latest studies of Centrum.

What is Xalkori?

Xalkori has active ingredients of crizotinib. eHealthMe is studying from 9,659 Xalkori users. Check the latest studies of Xalkori.

On Aug, 06, 2026

21 people who take Centrum and Xalkori together, and have interactions are studied.

What are the common drug interactions of Centrum and Xalkori, by gender? *:

female:

Cough
Blood thyroid stimulating hormone increased
Dyspnoea (difficult or laboured respiration)
Diarrhoea
Nausea (feeling of having an urge to vomit)
Constipation
Feeding disorder (when children refuse to eat certain food groups)
Oesophageal irritation
Paralysis
Viral infection

male:

Eye disorder
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Hypoaesthesia oral (reduced sense of touch or sensation in mouth)
Hypotension (abnormally low blood pressure)
Influenza like illness
Pneumonia
Neoplasm progression (growth of tumour)
Hypoacusis (loss of hearing)
Asthenia (weakness)
Blood sodium decreased

What are the common drug interactions of Centrum and Xalkori, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Asthenia (weakness)
Blood sodium decreased
Dyspnoea (difficult or laboured respiration)
Hypotension (abnormally low blood pressure)
Influenza like illness
Pneumonia

60+:

Cough
Blood thyroid stimulating hormone increased
Paralysis
Viral infection
Vocal cord disorder
Peripheral swelling
Blood albumin decreased
Fluid retention (an abnormal accumulation of fluid in the blood)
Hepatic enzyme increased
Non-alcoholic steatohepatitis (liver inflammation caused by a build up of fat in the liver)

What are the existing conditions these people have? *

Lung Neoplasm Malignant (cancer tumour of lung): 11 people, 52.38%
Osteoporosis (bones weak and more likely to break): 9 people, 42.86%
Lung Cancer - Non-Small Cell (lung cancer): 9 people, 42.86%
Migraine (headache): 6 people, 28.57%
Breast Cancer: 5 people, 23.81%
Pain: 5 people, 23.81%
Headache (pain in head): 4 people, 19.05%
Visual Impairment: 3 people, 14.29%
Hypersensitivity: 2 people, 9.52%
Constipation: 2 people, 9.52%

* Approximation only. Some reports may have incomplete information.

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